Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 207 for “"Synergistic effects"”.
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Synergistic Effects of Monoculture Biofilm Dispersion and Antibiotic Treatment
Bacterial biofilms have been identified as the causative agent of many infections, including catheter associated urinary tract infections (CAUTIs). While in a biofilm state, bacterial cells are less susceptible to antibiotic therapy. However, once released from a biofilm, antimicrobial …
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Synergistic effects between thiol collectors used in the flotation of pyrite
… flotation of pyrite at pH =4 and, secondly, why synergistic effects are observed, if any. The focus of the investigation was a 90:10 mole ratio mixture of PNBX and cyclohexyl DTC, although other collector ratios were compared in the batch flotation tests. This ratio was chosen to test the effect …
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Forces and Stability in Ternary Colloidal Systems: Evidence of Synergistic Effects
… has received very little prior study, namely synergistic effects that can arise in mixed colloidal systems in which the resulting force and stability of the system cannot be predicted using results obtained in more idealized systems consisting of fewer components. Two specific systems were …
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Pheochromocytoma-induced cardiomyopathy : a model of synergistic effects of multifactorial tumor secretions
… While one agent may dominate, its powerful effects are mediated by ancillary factors that alone may have no discernible action. We examined this paradigm by comparing catecholamine-infusion induced cardiomyopathy with the organ disease observed by catecholamine-secreting pheochromocytoma …
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Synergistic effects of mixtures of fungicides and medicinal plant extracts against Botrytis cinerea
… representing significant levels of in vitro synergistic interactions. Combinations of these components represent an attractive future prospect for the development of new management strategies for controlling B. cinerea. Since the in vitro tests of these mixtures showed inhibitory activity, …
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Characterization of the synergistic effects of cocaine with lateral hypothalamic brain stimulation reward
… is thought to exert its reward-relevant effects on neural circuitry that subsumes the rewarding effects of cocaine and natural rewards such as food. In the present experiments the curve-shift rate-frequency variant of the brain stimulation reward paradigm was used to characterize the …
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Individual and synergistic effects of lubricant additive (Ca, Mg, Zn) combinations on ash characteristics and DPF performance
… to be cleaned or replaced. While the detrimental effects of ash on DPF performance and therefore fuel economy can be illustrated and quantified, there is much to be understood about the specific factors that govern ash properties like distribution, permeability, and morphology. Several different …
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Synergistic effects of lubricant additive chemistry on ash properties impacting diesel particulate filter flow resistance and catalyst performance
… for filter removal and cleaning. The adverse effects of ash accumulation on DPF performance have been extensively studied in the past and are well know yet the underlying mechanisms for their presence are still not well understood. The ash which accumulates within a DPF is a product of a …
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Synergistic Effects Of Garcinol And Gemcitabine In Enhancing Therapeutic Efficacy In Pancreatic Adenocarcinoma Cells And Its Effect On Microrna Profile
<p>SYNERGISTIC EFFECTS OF GARCINOL AND GEMCITABINE IN ENHANCING THERAPEUTIC EFFICACY IN PANCREATIC ADENOCARCINOMA CELLS AND ITS EFFECT ON MICRORNA PROFILE</p> <p>By</p> <p>MANSI PARASRAMKA</p> <p>ADVISOR: DR. SMITI V. GUPTA</p> <p>MAJOR: NUTRITION AND FOOD SCIENCE</p> <p>DEGREE: DOCTOR OF …
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A Comparative Study of Synergistic Effects in Sequential Inactivation of Cryptosporidium Parvum Oocysts and Bacillus Subtilis Spores With Chemical Disinfectants
… has been provided for the occurrence/absence of synergistic effects observed in the inactivation of this parasite with sequential combinations of chemical disinfectants. The objective of this study was to investigate potential interactions among chemical disinfectants and oocyst constituents that …
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Synergistic effects of mixtures of the kresoxim-methyl fungicide and medicinal plants extracts in vitro and in vivo against Botrytis Cinerea
The fungus Botrytis cinerea is an opportunistic pathogen on a wide variety of crops, causing disease known as grey mould through infections via wounds or dead plant parts. Synthetic fungicides for controlling this disease are fast becoming ineffective due to the development of resistance. This, …
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Synergistic effects of mixtures of the kresoxim-methyl fungicide and medicinal plants extracts in vitro and in vivo against Botrytis Cinerea
The fungus Botrytis cinerea is an opportunistic pathogen on a wide variety of crops, causing disease known as grey mould through infections via wounds or dead plant parts. Synthetic fungicides for controlling this disease are fast becoming ineffective due to the development of resistance. This, …
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Combined Inhibition of Ddr1 and Cdk4/6 Induces Synergistic Effects In Er-Positive, Her2-Negative Breast Cancer With Pik3Ca/Akt1 Mutations
… INHIBITION OF DDR1 AND CDK4/6 INDUCES SYNERGISTIC EFFECTS IN ER-POSITIVE, HER2-NEGATIVE BREAST CANCER WITH <em>PIK3CA/AKT1</em> MUTATIONS</strong></p> <p>Maryam Shariati, M.S. Advisory Professor: Funda Meric-Bernstam, M.D.</p> <p>Molecular alterations in the phosphatidylinositol …
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The effects of light level and temperature on freshwater microbial biomass, production, enzyme activity, and community composition
… microbes in periphyton communities, but the synergistic effects of light and temperature on this phenomenon are not well understood and have implications on carbon cycling and energy flow. We employed recirculating mesocosms held at different temperatures and light levels and filled with …
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Small-molecule inhibition of general transcriptional regulators in cancer
… Here, I describe the cellular and molecular effects of inhibiting a general transcriptional regulator, CDK7, in T-cell acute lymphoblastic leukemia (T-ALL) cells. Because tumor cells commonly evolve resistance to individual therapies, I have also investigated the potentially synergistic …
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Sex and LRRK2 Genotype Differences in Inflammation and Dopaminergic Neurodegeneration in a Multi-Hit Model of Parkinson's Disease
… thesis was to explicate potential additive/synergistic effects of genetic LRRK2 anomalies and environmental risk factors as they pertain to motor behaviour, nigrostriatal dopaminergic degeneration, and neuroinflammation. Moreover, since the male sex represents a significant risk factor in …
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A pathways-based approach identifying determinants of drug resistance in oesophageal adenocarcinoma
… the mechanisms of action governing the synergistic effects identified. A model of cisplatin-resistance (OE33-CDDPR) was used to assess Src’s role in acquired resistance.<br/><br/>Results: <br/>GSEA identified pathways associated with resistance to chemotherapy in OAC. Candidate genes …
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Impact of Temperature and Microbial Infection on the Honey Bee Hemocytes
… coli) further deplete key hemocytes, revealing synergistic effects of environmental and pathogenic stressors. Beekeeping practices must prioritize hive temperature stability to mitigate immune risks. synergistic effects of environmental and pathogenic stressors. Beekeeping practices must …
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