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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 188 for “"Synaptic transmission"”.

  1. Physico-chemical analysis of synaptic transmission

    Mallanoo, TatsaneeUNSW, Sydney1978

    unsw Repository record

  2. Molecular Mechanisms Controlling Excitatory Synaptic Transmission

    Watson, Jake FrederickUniversity of Cambridge2019

    … neurotransmitter is released from the presynaptic cell and binds to postsynaptic receptors on another. In the case of excitatory synapses, the predominant neurotransmitter, L-glutamate, binds to postsynaptic AMPA receptors (AMPARs). Crucially, synaptic strength is plastic, and control of …

    cambridge Repository record

  3. NOVEL DOPAMINERGIC SIGNALING MODULATING HIPPOCAMPAL SYNAPTIC TRANSMISSION

    Rizvi, Nisha

    … functions and dysfunction of dopaminergic neurotransmission is thought to underlie numerous disorders, including schizophrenia, attention deficit hyperactivity disorder (ADHD), depression and Alzheimer’s disease. In the hippocampus, a dopaminergic projection from the ventral tegmental area (VTA) …

    siu-theses Repository record

  4. Modulation of synaptic transmission by TRP channels

    Jeffry, Joseph August

    … is the site where sensory afferent fibers make synaptic connections with second order neurons. Somatic and craniofacial afferents terminate in spinal cord dorsal horn (SDH) and caudal spinal trigeminal nucleus (CSTN). Neurotransmitter release from first order nerve terminals regulates ascending …

    siu-theses Repository record

  5. Synaptic transmission and integration in spinal motoneurones

    Clements, John D1986

    anu Repository record

  6. MeCP2 and the Epigenetic Regulation of Excitatory Synaptic Transmission

    Nelson, Erika Dawn2010

    … in both spontaneous and evoked excitatory synaptic transmission. Using pharmacological manipulations, we were able to attribute these deficits to the loss of transcriptional repression by MeCP2. By utilizing a conditional knockout approach, we found that these effects were not due to the …

    utswmed Repository record

  7. MODULATION OF SYNAPTIC TRANSMISSION AT THE NUCLEUS TRACTUS SOLITARIUS

    FENG, LIN2016

    … channels can modulate excitatory/inhibitory neurotransmission. I have designed studies to understand the role of nAChRs and TRP channels in the modulation of neurotransmission in the cNTS. In the first aim, experiments were designed to test the hypothesis that the cNTS contains function-specific …

    siu-theses Repository record

  8. Gene therapy for epilepsy: resculpturing synaptic transmission with neuropeptides

    Toft Sörensen, AndreasInstitutionen för kliniska vetenskaper, Lunds universitet2008

    … in the hippocampus by suppressing glutamatergic transmission. If manipulated, the NPY system may be capable of restoring the imbalance between excitation and inhibition occurring in the epileptic brain. Indeed, emerging evidence has established a proof-of-principle for viral vector-mediated …

    lund Repository record

  9. Cannabinoid regulation of excitatory synaptic transmission at hippocampal synapses

    Farah, AdhamUniversity of Dundee2021

    … of cannabinoid-mediated actions on excitatory synaptic transmission (Bajo et al., 2009). Therefore, the aim of this study was to investigate the effects of cannabinoids on excitatory synaptic transmission at different hippocampal CA1 synapses.<br/><br/>In this study, standard extracellular …

    dundee Repository record

  10. Effects of Temperature on Synaptic Transmission in Crayfish Muscle

    White, Roy LeeUniversity of Illinois at Urbana-Champaign2014

    Made available in DSpace on 2014-12-14T13:39:45Z (GMT). No. of bitstreams: 1 7915444.pdf: 5263669 bytes, checksum: b05e25afbdd255017067b8145a67ced3 (MD5) Previous issue date: 1979

    uiuc Repository record

  11. AMPA receptor diversity and dynamics during excitatory synaptic transmission

    Stockwell, ImogenUniversity of Cambridge2025

    … synapses, specialised into a pre and postsynaptic side. By employing AMPA receptors (AMPARs), the postsynaptic cell can respond to presynaptic glutamate release with millisecond-timescale precision. The diversity of AMPAR subtypes across the brain is vast, with each subtype providing …

    cambridge Repository record

  12. Age-dependent regulation of hippocampal excitatory synaptic transmission by leptin

    Mcgregor, GemmaUniversity of Dundee2018

    … leptin is a diverse regulator of hippocampal synaptic function (Irving and Harvey, 2014). Previous studies demonstrate that leptin can regulate hippocampal excitatory synaptic transmission in an age-dependent manner at Schaffer collateral (SC)-CA1 synapses (Moult and Harvey, 2011). In …

    dundee Repository record

  13. Estrogenic modulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses

    Clements, LeighUniversity of Dundee2020

    … to be an important modulator of hippocampal synaptic plasticity and function. The actions of estrogen at hippocampal Schaffer-collateral (SC)-CA1 synapses has been described in detail and at these synapses, estrogen can rapidly potentiate excitatory synaptic transmission (Oberlander and …

    dundee Repository record

  14. Role of the different domains of PSD-95 in basal synaptic transmission

    Bonnet, A.D. Stéphanie2012

    … mit Veränderungen in der Stärke der synaptischen Transmission. An exzitatorischen Synapsen in der CA1-Region des Hippocampus wird die synaptische Transmission imWesentlichen durch in der postsynaptische Verdichtung befindliche AMPA-Rezeptoren reguliert. Deren Funktion wird durch PSD-95 reguliert, …

    goettingen Repository record

  15. The Role of the Ras Guanyl-Nucleotide Exchange Factor Rasgrp1 in Synaptic Transmission

    Bungers, Simon2012

    … als auch in der Regulation der synaptischen Transmission und Plastizität. Die direkte Aktivierung von Ras Proteinen hat eine Vielzahl von möglichen Effekten zur Folge, was die experimentelle Erforschung von spezifischen Funktionen der Ras Signalwege sehr erschwert und in der Vergangenheit …

    goettingen Repository record

  16. Impact of Thalamocortical Synaptic Transmission on Input specific plasticity in Mouse Auditory Cortex

    Krishnan, RamyaGraduate Studies2012

    … field plasticity. Up and down regulation of synaptic strength, i.e. long-term potentiation (LTP) and long-term depression (LTD) of thalamocortical synaptic transmission is proposed as an underlying mechanism for such cortical plasticity. To date, auditory thalamocortical synaptic plasticity …

    calgary Repository record

  17. I. Advanced Fluorescent False Neurotransmitters for the Study of Monoamine Transporter Activity and Synaptic Transmission

    Karpowicz, Richard2013

    … activity and distribution, as well as synaptic transmission in the brain. The second section details early studies concerning experimental therapeutics recently identified by our group to induce the synthesis and release of Glial Derived Neurotrophic Factor (GDNF) from a model …

    columbia-diss Repository record

  18. Angiotensin II modulates glutamate-induced depolarizations and synaptic transmission in rat locus coeruleus neurons in vitro.

    Xiong, Huangui.University of Ottawa (Canada)2009

    … AII was also found to depress responses to synaptically released excitatory amino acids (EAAs). In fact we were able to show that excitatory postsynaptic potentials (EPSPs) evoked by electrical stimulation were blocked by Glu receptor antagonists, indicating involvement of EAAs in the …

    ottawa-retro Repository record

  19. Role of galanin in synaptic transmission and plasticity in the CA1 area of the rodent hippocampus

    Coumis, UraniaThe University of Edinburgh2005

    … in vivo. The sustained increase in glutamatergic synaptic strength following high frequency stimulation of hippocampal neurones, a phenomenon termed long-term potentiation (LTP), has been widely recognised as a model ofthe synaptic changes that may underlie learning and memory in vertebrates. It …

    edinburgh Repository record

  20. Modulation of hippocampal synaptic transmission by the peptide diazepam binding inhibitor and optogenetic manipulation of astrocytes

    Courtney, Connor DukeUniversity of Illinois at Urbana-Champaign2021

    Hippocampal synaptic transmission is an intricate and flexible entity that can be modulated, both directly and indirectly, by a variety of different signaling molecules and cell types. The peptide diazepam binding inhibitor (DBI) has complex physiological functions and is capable of both enhancing …

    uiuc Repository record

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