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Showing 1 to 1 of 1 for “"Synapse protection"”.

  1. Evaluating the Therapeutic Effect of an Hsp90 Inhibitor in Mouse Models of Alzheimer’s Disease

    … by qRT-PCR) select proteins enriched in the synapse, such as Post-synaptic density 95 (PSD95), synapsin I, and brain-derived neurotrophic factor (BDNF), among others. Confocal imaging demonstrated rescued dendritic spines with 17-AAG treatment after Aβ challenge in neuronal culture models. …

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