Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 56 for “"Symptom onset"”.
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From Symptom Onset to Diagnosis:a critical exploration into the experiences of young people with Juvenile-onset Systemic Lupus Erythematosus
… in the UK (Papadimitraki & Isenberg 2009). Symptoms include fatigue, tiredness, malar rash, joint problems, headaches and kidney problems. There is a paucity of literature relating to the experiences of young people before and during diagnosis of JSLE. An understanding of young people’s …
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Rate and predictors of decline in dementia of the Alzheimer type as measured by the hierarchic dementia scale (HDS)
… Scale (HDS) based on the risk factors of age of symptom onset, education, gender, and place of residence. It was hypothesized that younger age of symptom onset would predict a faster rate of decline on the total HDS score and in the seven cognitive domains of orientation, language, memory, …
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Access to acute stroke care: a description of stroke patients' journey to a district hospital
… to describe the factors that influence time from symptom onset to hospital arrival in patients that present to a district level hospital Emergency Centre with confirmed ischaemic strokes. Methods A descriptive analysis was performed using retrospective folder and database review. All adult …
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The Apoptotic and Wallerian Degeneration Pathways Regulate Disease Onset and Progression in the SOD-1G93A Transgenic Mouse Model of ALS
… Bax delays muscle denervation, prolongs disease onset, prevents motor neuron cell death and improves survival in an ALS mouse model. However, the timing and extent of axon degeneration in these mice is unaffected. Here, we examine the role of Sarm1, a component of the Wallerian degeneration …
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Predictive models of tissue outcome in acute human cerebral ischemia using diffusion and perfusion weighted MRI
… cerebral ischemia are typically based on time of symptom onset, limiting the number of patients treated. Imaging, however, offers insight into the physiologic integrity of brain tissue that is not attainable with time of symptom onset alone. This thesis extends existing imaging techniques for …
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Time to Medical Help-Seeking for Adults Who Experience Symptoms of Stroke in a California-Mexico Border Region
… must be administered within 4.5 hours of stroke symptom onset. Despite its proven efficacy fewer than 12% of those suffering acute ischemic stroke receive this treatment. The most common reason for low utilization is late medical help-seeking. Though the relationship among predictor variables and …
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Understanding the gender-based mechanism of mso in als mice: a metabolic characterization of the sod1-g93a mouse model
… atrophy. Patients become paralyzed shortly after symptom onset and typically die within one to five years of pulmonary complications. ALS is a relatively rare disease, with an overall incidence of approximately 2 in 100,000 people per year and a prevalence of about 5 in 100,000 people. It is …
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Myasthenia Gravis mimics: An audit of cases identified at Groote Schuur Hospital over 20 years
… (1996 to 2017) by final diagnosis, the age at symptom onset, the time delay and clues which led to the final diagnosis. Results: There were 31 cases identified; 10 were probable congenital myasthenic syndromes (CMS), 6 functional neurological symptoms (FNS), 6 motor neuron disease (MND) …
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The Use of Ischemia-modified Albumin(IMA) in Ischemic Stroke
… emergency patients with acute neurologic symptoms were admitted to the emergency department within 6 hours of symptom onset (28 Ischemic Stroke Group; SG, 24 Non-Stroke Group; NSG). Blood samples for IMA measurements by albumin cobalt binding test (Ischemia Technology, Denver, U.S.A) were …
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STEMI Management and Outcomes at a Regional Hospital in Guatemala
… in both groups with survivors showing longer symptom-onset-to-door and door-to-ECG time intervals. Survivors had markedly longer symptom‑onset‑to‑door times than non‑survivors (23.96 ± 27.11 vs 1.27 ± 0.70 hours), whereas non‑survivors received faster in‑hospital ECGs (21.36 ± 10.82 vs 46.8 ± …
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The Best Practice Guideline for Early Detection and Treatment of Heart Disease In Asymptomatic Adults with a Family History of Premature Coronary Artery Disease
… for early detection and treatment of CAD in asymptomatic adults with a family history of premature CAD for the prevention of severe coronary events prior to symptom onset. The purposes of this evidenced based project were to (a) review the literature on the significance of family history of …
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Development of tools for automated collection, integration and analysis of genetic data in ALS
… typically leads to death within 3-5 years of symptom onset. Understanding what causes ALS has been a challenge, but more research in this area, enhanced by advanced technology like high-throughput next generation sequencing, is paving the way for better information and direction. The volume of …
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Synaptic morphology, function, and regulation in a paediatric-onset neurodegenerative disorder
… of heparan sulphate. Progressive neurological symptoms are the primary manifestation, including impaired control of motor function. Despite the abnormal intracellular pathology, negligible neuronal cell loss occurs. This suggests that neurological dysfunction does not arise from cellular loss, …
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Prodromal Symptoms of Depression: Tests of a Model of the Development and Remission of Depressive Symptoms
… for the development and remission of depressive symptoms. In this model, prodromal symptoms emanate from the core pathological processes underlying the disorder and comprise the core syndrome as the earliest symptoms to appear, with episodes of depression representing the more pronounced peaks of …
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Albumin Therapy in Acute Stroke Patient
… either 40 g or 80 g of albumin within 24 h from symptom onset. The National Institutes of Health Stroke Scale (NIHSS) and diffusion-weighted imaging (DWI) were serially checked. There was no adverse effect related to albumin therapy. Although there was no significant difference in both baseline …
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“That was menopause, but I didn't know that” Understanding Family Systems of Menopause Knowledge among African American Women with Endometrial Cancer
… study seeking to characterize the experiences of symptom onset and diagnosis of African American women who have been diagnosed with endometrial cancer. In-depth, qualitative interviews from thirteen African American women who received a diagnosis of endometrial cancer were examined using thematic …
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A One-Week Intensive Treatment Program for Pediatric Obsessive-Compulsive Disorder
… as many as 50% of individuals with OCD report symptom onset before age 15. Despite the growing evidence supporting the efficacy of Exposure and Response Prevention (ERP) for youth with OCD, children seeking services for their OCD symptoms often do not receive ERP. Intensive treatment programs …
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Predictive modeling of postpartum depression risk using electronic health record data
… PHQ-9, are primarily reactive and rely on the onset of clinical symptoms. This study aimed to develop machine learning (ML) models to proactively predict PPD risk utilizing multidimensional electronic health record (EHR) data and to identify key predictive risk factors. A retrospective analysis …
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Peripheral Leukocytes and Intracerebral Hemorrhage
… to the emergency department within 12 hours of symptom onset. Absolute monocyte count, a readily available and ubiquitous biomarker at presentation in ICH patients, may represent a novel prognostic tool after ICH.
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Getting to the Doctor: BPSS Factors of Health Care Utilization in Fragile Families
… access and utilization that may occur prior to symptom onset or illness diagnosis and treatment. The Family Systems-Genetic Illness Model expands the Biopsychosocial-Spiritual model to include the time period prior to illness diagnosis (Rolland & Williams, 2005). Using data from the Fragile …
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