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Showing 1 to 1 of 1 for “"Switch transcripts"”.
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The Role of RNA Helicase RHAU in Immunoglobulin Class Switch Recombination
… isotypes through a process known as class switch recombination (CSR). In these cells, activation induced cytidine deaminase (AID) binds Gquadruplex (G4) switch transcripts, which serve as guide RNAs to target AID to the immunoglobulin heavy chain switch (S) regions in the DNA for CSR. …