Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Sustain release"”.
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Study of controlled release of active pharmaceutical ingredients from functionalized nanoclays and polymer matrices
… segment of this research focused on the API release from the ternary system (API/clay/polymer) produced by hot melt mixing. A novel approach in order to have a sustained API release by utilizing the nanoclays was attempted. Since the API present in the clay interspacing may experience one …
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Pentablock copolymers based controlled release formulations of small and macromolecules for ophthalmic applications
… compositions were evaluated to optimize drug release profile from nanoparticles and thermosensitive gel formulations. Our composite approach i.e. pentablock copolymers based nanoparticles suspended in thermosensitive gel provided sustained zero-order delivery of encapsulated therapeutic agents …
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Effects of Advancing Age on ER Calcium Regulation in Rat Superior Cervical Ganglia
<p>Intracellular calcium ([Ca<sup>2+</sup>]i) release from endoplasmic reticulum (ER) stores plays an important role in cell signaling. These stores are rapidly refilled via voltage-gated calcium channels or spontaneously via store-operated calcium channels and subsequent pumping by ER …
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Mucoadhesive buccal tablets for the delivery of nicotine and Delta9-tetrahydrocannabinol.
… of existing NRT treatments. Controlled release layers were prepared using crystalline nicotine hydrogen tartrate salt in a dry blend with adhesive and controlled release excipients. Powder blends were compressed to form 6 mm tablets. Release profiles indicated that a combined matrix of …
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Biodegradable Polymeric Biomaterials in Different Forms for Long-acting Contraception and Drug Delivery to the Eye and Brain
… of poor solubility, low permeability and sustained release owing to the advantages of biocompatibility, versatility, and tunable drug release. Polyesters and polysaccharides are the most common polymers that were explored for drug delivery applications because of their unique advantages …