Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Susceptibility factor"”.
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Molecular analysis of decay accelerating factor as a potential susceptibility factor to developing treatment resistant extraocular muscle involvement in Myasthenia Gravis
… injury at the NMJ. Decay Accelerating Factor (DAF), a member of complement regulatory proteins, prevents activation of autologous components of complement pathways. The absence of DAF, in knock-out mouse models, has been shown to significantly increase the susceptibility to experimental …
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Investigation into the function of Pi17316, a novel effector protein from <i>Phytophthora infestans</i> that compromises plant immunity
… colonisation. VIK itself was shown to be a susceptibility factor, required for full P. infestans colonisation. Overexpression of StVIK results in the suppression of INF1 and R2/Avr2 responses and enhances P. infestans ability to colonise the host. Furthermore, silencing of NbVIK attenuates …
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Exploiting crosstalk between growth and immunity in plants : the role of the <i>Phytophthora infestans</i> effector AVR2 in potato late blight
… S. tuberosum.<br/><br/>StBSL1 is shown to be a ‘susceptibility factor’ in P. infestans infection – a host protein with a positive effect on pathogen virulence. AVR2 stabilises BSL1 in planta, and both AVR2 and BSL1 are shown to suppress primary defence responses in the …
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The role of autophagy in arabidopsis thaliana during biotrophic and hemibiotrophic fungal infections
… that the autophagy pathway is a potential host susceptibility factor for pathogen infection, possibly involved in establishing/facilitating biotrophy in A. thaliana.
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The Effects of ALAD Genotype and Blood Lead Levels on Anthropometric Measures in a Cohort of Mexican Children
… this relationship may depend on the presence of susceptibility factors, including genetic variation. Blood lead levels (BLL) differ between groups with different variants of the ALAD gene, which encodes the enzyme aminolevulinic acid dehydratase (ALAD) that participates in heme synthesis. We …
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Characterization of interleukin-4 induced gene-1 (IL-4I1) as a host immunoregulator to cutaneous leishmaniasis in cell based models
… this underscores IL-4i1 as a potential susceptibility factor to CL. Understanding how Leishmania parasites can modify host immune response could lead to identifying novel therapeutics such as host-directed therapies.
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A molecular genetic analysis of resistance to poleroviruses in sugar beet and oilseed rape
… identified the resistance as ‘passive’, where susceptibility was dominant, and conditioned by a monogenic trait. This study began by characterising the gene responsible for susceptibility by bulked segregant analysis and AFLP™. This identified a region of ca. 5Mbp region on A. thaliana …
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Cloning and characterization of th BPR1 gene ('Botrytis cinerea and Pseudomonas syringae pv. phaseolicola susceptibility and Root length 1') from Arabidopsis thaliana
… (At1g05340) was found to be associated with susceptibility to pathogens and altered root length and was chosen for further in-depth study. The locus was renamed “BPR1” (Botrytis and Pseudomonas syringae pv. phaseolicola susceptibility and Root length). BPR1 expression was very low in …
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Arbitrary associative memory: a candidate cognitive endophenotype for probable Alzheimer's disease
… AD or “probable AD”. As far as genetic risk factors are concerned, the apolipoprotein E epsilon-4 allele is the only reliable genetic susceptibility factor for probable AD. The investigation of cognitive endophenotypes for probable AD, or cognitive markers of liability to the condition that …