Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 282 for “"Surface plasmon resonance"”.
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Particle-modified Surface Plasmon Resonance Biosensor
Surface plasmon resonance (SPR) biosensors have attracted great attention in scientific research in the past three decades. Extensive studies on the immobilisation of biorecognition elements have been conducted in pursuit of higher sensitivity, but trialled formats have focussed on a thin layer …
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Ultrasonic agitation for surface plasmon resonance biosensors
… and ability to yield a localised surface plasmon resonance, surface-based nanoparticles have gained popularity in various biosensing applications. In such configurations, fluid containing biological material such as proteins is injected into a static cell containing the sensing …
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Integrated optical surface plasmon resonance for electrochemically addressed layers
… the development of the first integrated optical surface plasmon resonance sensor that combines an optical and electrochemical interrogating technique in sensing electrochemically addressed layers over a gold film. This device brings together the advantages of the analytical technique of surface …
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Localized Surface Plasmon Resonance: Nanoscale Sensing for Processes at Interfaces
This PhD thesis reports the use the emerging surface-sensitive optical technique of localized surface plasmon resonance (LSPR) to characterize the interaction of relevant classes of biomolecules, e.g. peptides, proteins, lipids and DNA strands, at solid-liquid interfaces, with an emphasis on …
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Electrochemical impedance spectroscopy and surface plasmon resonance for diagnostic antibody detection
… is high. Evanescent field biosensing, e.g. Surface Plasmon Resonance (SPR), and electrochemical detection, in particular Electrochemical Impedance Spectroscopy (EIS), have been shown viable for detection of lower affinity antibodies, based on the principle that these technologies allow the …
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Creation of novel gold-nanorod-based localized surface plasmon resonance biosensors
Starting with a comprehensive review of both surface plasmon resonance (SPR) based and localized surface plasmon resonance (LSPR) based sensors, this thesis reports the studies on the development of a novel sensitive gold nanorod (GNR) based label-free LSPR optical fibre biosensor, and the …
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Multiwavelength Surface Plasmon Resonance Sensor Designs for Chemical and Biochemical Detection
Surface plasmon resonance (SPR) sensors using multiwavelength light coupling are investigated to probe changes in refractive index that occur as a result of chemical or biochemical processes. Traditional SPR sensors have used angle modulation to facilitate detection at the sensor surface; however, …
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Three-photon Absorption Process In Organic Dyes Enhanced By Surface Plasmon Resonance
… three-photon absorption processes by means of Surface Plasmon. We demonstrated an enhancement of the effective two- and three-photon absorption cross-section of an organic compound of 480 and 30 folds, respectively. We proved that the enhancement is a direct consequence of the electric field …
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Development of High Pressure Surface Plasmon Resonance for the Study of Biosystems
… shown that BIAcore(TM) SA chips maintain their surface binding functionality after pressure exposure and that effects to the surface are reversible to 6000 psi. Three test systems were chosen to be studied using this instrument, each having different characteristics; cytochrome c association to …
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Investigations into Protein-Surface Interactions via Atomic Force Microscopy and Surface Plasmon Resonance
Protein surface interactions are important in many diverse applications. In this dissertation nonspecific and specific interactions of two proteins (fibrinogen and F1-ATP synthase) with a variety of surfaces have been investigated via atomic force microscopy and surface plasmon resonance. Chapter …
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Surface Plasmon Resonance Imaging Biosensors for Cancer Diagnosis: Detection of Circulating Tumor DNA
… doctoral thesis focused on the realization of Surface Plasmon Resonance Imaging (SPRI) biosensor for the rapid, simple and label-free detection of single point mutations in the KRAS gene, standard actionable cancer biomarkers for colorectal cancer, in human plasma samples. Initially, the SPRI …
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A chemical sensor based on surface plasmon resonance on surface modified optical fibers
… is described which utilizes the phenomenon of surface plasmon resonance to detect changes in refractive index of chemical or biochemical samples applied to a surface modified optical fiber. The sensor is constructed by polishing a short section of the lateral surface of an optical fiber to its …
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SURFACE PLASMON RESONANCE IMAGING BIOSENSORS FOR THE DETECTION OF PATHOGENS AND TOXINS IN FOOD
… In particular, optical biosensors based on Surface Plasmon Resonance Imaging (SPRI) are attractive because they allow the sensitive detection of analytes from food matrices in real-time. SPRI can assays crude samples without purification and can exploits antibodies or single-stranded DNA …
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Optical fibre surface plasmon resonance sensors based on a metallic array of sub-wavelength apertures
In this dissertation, optical fibre surface plasmon resonance sensors based on a metallic array of sub-wavelength apertures are investigated. Metallic sub-wavelength apertures may be designed to support surface plasmon resonances that are sensitive to the surrounding environment when embedded at …
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Real Time Biological Threat Agent Detection with a Surface Plasmon Resonance Equipped Unmanned Aerial Vehicle
… that made UAV integration a feasible task. A Surface Plasmon Resonance (SPR) biosensor was integrated for the first time into a small UAV platform, allowing the UAV platform to collect and then quantify the concentration of an aerosolized biological agent in real-time. A sensor operator ran …
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Detection of a Surrogate Biological Threat Agent (Bacillus globigii) with a Portable Surface Plasmon Resonance Biosensor
… different species of Bacillus using a portable surface plasmon resonance (SPR) biosensor (SPIRIT 4.0, Seattle Sensor Systems). Two methods (direct capture and antibody injection) were used to determine the limit of detection for spores of B. globigii and to detect spores of B. globigii in a …
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Studies of polysaccharide adsorption onto model cellulose surfaces and self-assembled monolayers by surface plasmon resonance spectroscopy
… at the air/water and solid/water interfaces, surface tension measurements and surface plasmon resonance (SPR) spectroscopy have been identified as key methods for the acquisition of structural and thermodynamic information. These techniques were used to determine air/water and cellulose/water …
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Surface-enhanced Raman and surface plasmon resonance measurements of Case II diffusion events on the nanometer length scale
A study of spatially-localized phenomena associated with Case II transport is reported. Steady-state aspects of viscoelastic diffusion were investigated with the aid of SERS-active planar films implanted in $\mu$m-scale polymer films. The use of Au rather than Ag metal-island films is shown to …
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