Global ETD Search
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Showing 1 to 2 of 2 for “"Supratentorial Ependymoma"”.
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Novel Diagnostics and Therapeutic Approaches for Supratentorial Ependymoma
Ependymoma is the third most common paediatric brain tumour. These tumours are incurable in up to 40% of cases. Previously classified as a single disease by histological criteria, ependymomas are now grouped into nine molecular subgroups, three in each compartment of the central nervous system. The …
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Molecular Mechanisms of C11orf95 translocations in cancer.
… have previously described the genetic driver of supratentorial (forebrain) ependymomas as translocations of the C11orf95 gene of unknown function and RELA, the canonical nuclear effector of NF-B signalling. Subsequent studies have reinforced our original findings on the frequency (>70%) of these …