Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Suppressor of Fused"”.
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SUFU in SHH signalling mediated myogenesis
Myogenesis is defined as the formation of skeletal muscle tissue during embryonic development and involves a multitude of cellular signalling pathways. Among these include the Sonic hedgehog (Shh) signalling pathway which must be deactivated for differentiation into muscle cells to occur. However, …
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Caractérisation des mécanismes inhibiteurs de la voie de signalisation Hedgehog dans les cancers du côlon
… HIP (Hedgehog interacting protein), SuFu (Suppressor of Fused) et ZIC 2, ont été étudiées dans les cancers du côlon. HIP est exprimé dans deux lignées de cancers du côlon sur sept et semble être sous-exprimé dans quatre tumeurs primaires de côlon sur huit par rapport aux tissus sains …
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Regulation of morphogen signalling during neural patterning in the Xenopus embryo
… to ensure body axis development and formation of the central nervous system. We first show that the intracellular cytoplasmic protein XSufu acts as a dual regulator of Hedgehog (Hh) and Wnt signals during neural induction and patterning in the Xenopus embryo. We further reveal an essential role …