Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Suppressor of Cytokine Signaling 1"”.
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Investigation of the Efficacy of a Novel CsA Formulation Alone or in Combination with Cell Therapy in a Humanised Mouse Model of GvHD
The immunomodulatory ability of mesenchymal stromal cells (MSC) make them an ideal cellular therapy for inflammatory diseases such as acute Graft versus Host Disease (aGvHD). Cyclosporine (CsA) is an immunosuppressive drug commonly used as prophylaxis and treatment of aGvHD. However, oral …
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A Dual-Domain Peptide Strategy for Targeted Regenerative Repair
… kinase inhibitory region derived from suppressor of cytokine signaling 1 (SOCS1; KIR), fused to a TAT cell-penetrating peptide (KIR-TAT) to promote intracellular delivery and attenuation of pro-inflammatory signaling pathways. Collectively, this dual-domain design seeks to confine …