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Showing 1 to 20 of 51 for “"Superparamagnetic iron oxide"”.
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Engineering Superparamagnetic Iron Oxide Nanoparticles for Environmental Applications
<p>Engineered, superparamagnetic iron oxide nanoparticles (IONPs) have drawn considerable research attention for a broad range of applications based on tunable size and shape, surface chemistries, and magnetic properties. For successful aqueous-based, environmental applications, it is necessary to …
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Magnetic resonance thermometry with superparamagnetic iron oxide nanoparticles
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-05-01
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Thermally Responsive Peptide Coated Superparamagnetic Iron Oxide Nanoparticles for Drug Delivery
… sites and trigger drug release. In this context, superparamagnetic iron oxide nanoparticles based drug delivery systems are highly desirable. Superparamagnetic iron oxide nanoparticles upon exposure of alternate magnetic field could be directed and provide heat to localised areas. Moreover, …
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Development of Novel Synthetic Methods for Size-Tunable Synthesis of Superparamagnetic Iron Oxide Nanoparticles
… published, although the thermal decomposition of iron(III) precursors in organic solvents has been shown to yield high quality particles with low shape and size dispersity. Currents methods lack reproducibility resulting from non-stoichiometric starting materials, and reliance on reaction …
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Sol-gel matrix-mediated synthesis of superparamagnetic iron oxide clusters and supported iron porphyrin oxidation catalysts
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1998.
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Purification of human dna for dna profiling from body fluid contaminated soil using superparamagnetic iron oxide nanoparticles (spions).
… extraction method, and a method employing superparamagnetic iron oxide nanoparticles (SPIONs) generated in-house. Extraction success and level of purity of the human DNA extracted using these methods were assessed by quantifying the amount of DNA recovered using a Nanodrop 2000 and the …
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Fundamental studies and applications for the development of novel MRI contrast agents: Hyperpolarized xenon-129 and superparamagnetic iron oxide nanoparticles
… contrast agents: hyperpolarized 129Xe gas and superparamagnetic iron oxide nanoparticles (SPIONs). The largest `Achilles' Heel' of MR techniques is their inherent lack of detection sensitivity due to the exceedingly small magnitude of the nuclear spins, giving rise to small thermal …
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Magnetic targeted drug delivery system in gene therapy
… covers the synthesis and characterization of superparamagnetic iron oxide nanoparticles and summarizes the research process of polymeric coating as a function of gene vectors. Nuclear magnetic resonance technology is used to identify the structure of the polymer step by step. At last, the use …
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Composite Nanoparticle Materials for Electromagnetics
… is the magnetic core, usually made of soft iron. Further, losses due to eddy currents and magnetic remnance occur in soft iron cores. This thesis discusses the different materials suitable that might be to replace soft iron in electromagnetic devices, Methods developed to fabricate different …
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Removal of organic pollutants present in water using inorganic-organic Hybrid Multifunctional Nanocomposites
… nanocomposites (synthesised by embedding superparamagnetic iron oxide and titanium dioxide into a carbon source i.e. Multi walled carbon nanotubes and activated charcoal) The second type are Novel hybrid Magnetic Ionic-liquid-nanocomposites were synthesised with silica coated magnetic …
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Synthesis and development of hydrophilic iron oxide nanoparticles for biomedical applications
Uniformly sized superparamagnetic iron oxide nanoparticles (SPIONs) with inorganic diameters of 3-35 nm were synthesized. New surface ligand coatings were designed and synthesized, and the resulting hydrophilic SPIONs in biological buffers were found to be compact, stable, highly magnetic, and …
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Detection and Quantification of Cells using Magnetic Particle Imaging and Magnetic Microspheres
… imaging modality that specifically detects superparamagnetic iron oxide nanoparticles (SPIOs). Our lab has shown that cell tracking with magnetic resonance imaging (MRI) has very high sensitivity, but low specificity and quantification of iron labeled cells is difficult. MPI cell tracking …
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Synthesis, Characterization, and Evaluation of Silica-Nanosphere-Based Contrast Agents for Biomedical Application
… dual modality nanospheres were developed using superparamagnetic iron oxide particles. The agglomeration problems of iron oxide nanoparticles were resolved with an ultrasonication process and then ultimately settled by encapsulating within a silica shell. The surface of silica shells were …
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Evaluation of nanoparticles-based thermotherapy for cancer
Under alternating magnetic field, superparamagnetic iron oxide nanoparticles can be used to generate heat for the treatment of cancer. With suitable coating, these nanoparticles are biocompatible, stable in solution, and absorbed by tumor cells in good contrast. The mechanism of heating is mainly …
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Development of Multifunctional Nanoparticles for Cancer Therapy Applications
… perform specific objectives in a biological environment. The nanoparticles examined include carbon nanotubes (CNTs), superparamagnetic iron oxide nanoparticles and superparamagnetic iron oxide nanocomposites. The unique nanomaterials have been developed to address continued issues in cancer …
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Innovating surgery for oral squamous cell carcinoma with targeted fluorescent and magnetic tracers
… molecular imaging, and FerroTrace, a superparamagnetic iron oxide nanoparticle (SPION) that has been engineered with mannose end targets for macrophage-specific binding to aid SLNB.
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Investigation of Metal-Dependence in DNAzymes and Applications of DNAzymes and Aptamers for Diagnostics
… aptamer technology was also combined with superparamagnetic iron oxide nanoparticles, to make MRI contrast agents which showed a change in contrast upon binding target analytes, adenosine and thrombin, which is a first step towards developing aptamer-based contrast agents for molecular MRI, …
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Magnetic particle imaging for intraoperative breast cancer margin assessment and functional brain imaging
… uniquely images the nonlinear magnetization of superparamagnetic iron oxide nanoparticles (SPIOs). MPI boasts high sensitivity, zero background signal, positive contrast, fast temporal resolution, and quantitative detection. The field of MPI is currently preclinical, and this work aims to scale …
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Design and Development of Calcium Sensitive Contrast Agents for fMRI
… sensors for MRI based on the conjugation of superparamagnetic iron oxide nanoparticles (SPIOS) to calcium sensing protein calmodulin and its target peptides. In the presence of calcium, interaction between the two protein domains drives the aggregation of SPIOs which results in up to four …
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A Compressed Sensing Approach to Detect Immobilized Nanoparticles Using Superparamagnetic Relaxometry
<p>Superparamagnetic relaxometry (SPMR) is an emerging technology that leverages the unique properties of biologically targeted superparamagnetic iron oxide nanoparticles to detect cancer. The use of ultra-sensitive sensors enables SPMR to detect tumors ten times smaller than current imaging …
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