Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Sulphonamides"”.
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Thiazolidinone-isatin hybrids as multi-target anticancer agents
… and pursuing in our ongoing work on benzene sulphonamides isatin-thiazolidinone hybrids as inhibitors of hCA IX and hCA XII, four series of molecules were successfully synthesized and characterized. Biochemical tests performed on hCA I, hCA II, hCA IX, and hCA XII isoforms have shown …
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Single-Payload Bioconjugation to Native Antibodies And A General Method for the Self-Immolative Release of Amide-Containing Molecules
… further exploitation of the method for sulphonamides. Urea and thioamide release was also attempted but proved synthetically challenging. The utility of amide release was demonstrated by its successful application in the targeted release of linezolid from a prodrug using the …
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Resistencia a beta-lactámicos y fluoroquinolonas en Salmonella enterica. Mecanismos moleculares y elementos de movilización génica
… to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT, 29.5%). Low resistance percentages of resistance to ciprofloxacin or third generation cephalosporins were observed. The second objective was to characterize the mechanisms of resistance to betalactams (and to …
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Epidemiology of antimicrobial resistance at the livestock-human interface in an urban environment: a One Health approach
… human antimicrobials while tetracyclines, sulphonamides, penicillins, and macrolides were the most commonly purchased veterinary antimicrobials. This finding was in line with the resistance phenotypes and genotypes described in this thesis. I found that whilst most pharmacists were …
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Reductive cleavage of N-substituted benzenesulfonamides and p-sulfamylbenzoic acid
<p>The objective of the present work was to study further the effect of varying substituents on the nitrogen atom and on the ring of sulfonamides in the Birch reduction of aromatic sulfonamides, especially with respect to the amount of thiol formed, in the hope that information concerning the …
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Phosphodiesterase 4 inhibitors for the treatment of inflammation associated with respiratory disease
… The drug classes examined were xanthines, aryl sulphonamides, quinolones, 7-methoxybenzofuran-4-carboxamides, and 7-methoxyfuro[2,3-c]pyridine-4-carboxamides. The lead molecules selected in each publication had improved PDE4:RBA ratios which translated into an improved therapeutic window in …
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Skysčių chromatografija–tandeminė masių spektrometrija antibiotikų nustatymui maisto produktuose /
High–performance liquid chromatography (HPLC) and/or ultra-performance liquid chromatography (UPLC) techniques coupled with tandem mass spectrometry (MS/MS) were developed for the determination of common antibiotics (chloramphenicol, sulfonamides and nitroimidazoles together with their metabolites) …