Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Sulfhydryl Reagents"”.
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The emerging role of the a4(+)a4(-) interface as a determinant of functional signatures of a4ß2 nicotinic acetylcholine receptors
… modification of the substituted cysteine with sulfhydryl reagents. These findings suggested that agonist occupation of the site at the a4(+)/a4(-) interface leads to channel gating through a coupling mechanism involving a conformational switch in loop C. The sulfhydryl reagents had similar …
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Structural and functional relationship of photosynthetic bacterial reaction centers
… reaction centers (RCs) was modified with various sulfhydryl reagents. It was found that mercurial reagents, especially p-chloromercuribenzenesulfate (pCMBS), inhibit Q$\sb{\rm B}$ function in RCs from Rhodobacter sphaeroides and Rhodobacter capsulatus, but not in Rhodopseudomonas viridis. By …
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Exploring the Dynamics of Mechanosensitive Channels Utilizing a Post Translational Modification Approach
… allows us to use Methanethiosulfonate (MTS) sulfhydryl reagents that can form disulfide bonds with cysteines to change the properties (charge or hydrophobicity) of specific residues. We then use the double knockout strain, ∆MscL/∆MscS, which is osmotically fragile and has a reduced viability …
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The penetration protease of the cercariae of Schistosoma mansoni
… or phenylmethylsulfonyl fluoride, but not by the sulfhydryl reagents iodoacetamide or p-chloromercuribenzoate. Typical trypsin inhibitors such as soy bean trypsin inhibitor, trasylol or benzamidine inhibited the enzyme to a lesser degree. The active-site labels, TLCK, TPCK and AcAAAACK of trypsin, …
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Purification and characterization of malate dehydrogenase and 6- phosphogluconate dehydrogenase from Haemophilus influenzae
… whereas no inactivation was observed with sulfhydryl reagents. Haemophilus influenzae 6-phosphogluconate dehydrogenase was purified 308-fold with a 16% recovery through a 4-step chromatographic procedure involving a PhenylSepharose hydrophobic column, and affinity chromatography on Matrex …
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Animal and Plant Viruses with Double-Stranded Ribonucleic Acid
… groupings on reovirus 3 are sensitive to sulfhydryl reagents; they are also sensitive to trypsin, but resistant to chymotrypsin; they have the ability to react with neuraminic acid-containing glycoprotein receptors, but lack neuraminidase activity. The reproductive process of reovirus 3 is …
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Mechanistic Studies on Memory of Chirality Alkylations of 1,4-Benzodiazepin-2-ones & Structure-based Design of Insecticidal AChE Inhibitors for Malaria Mosquito, Anopheles gambiae
Memory of chirality (MOC) is an emerging strategy for asymmetric synthesis which relies upon the intermediacy of transiently non-racemic reactive species. In these reactions the configuration of the sole stereogenic center of the enantiopure starting material is "memorized" by a chiral non-racemic …