Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Sulf1"”.
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Role of heat shock protein 70 and sulphatases 1 and 2 in apoptosis induced by cytotoxic cells of the immune system
… Apoptose führt. Die Defizienz der Sulf1- und Sulf2-Gene, die für die Sulphatasen 1 und 2 kodieren, welche das Sulphatierungsmuster von Zellen modifizieren, könnte einen Effekt auf die Effizienz der CTL-vermittelten Apoptose haben, weil Sulf-defiziente Zellen ein erhöhtes …
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Elucidation of gene clusters underlying withanolide biosynthesis in ashwagandha
… (CYP88C7 and CYP88C10) and a sulfotransferase (SULF1) generate the characteristic A-ring structure of withanolides, featuring a C₁ ketone and C₂-C₃ unsaturation. The discovery of SULF1 as a core withanolide pathway enzyme challenges the conventional view of sulfotransferases as tailoring enzymes …
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Decoding structure-function relationships of glycans
… activity in breast cancer. Here, we report that SULF1, an HSGAG modifying enzyme, is required for efficient tumor initiation, growth and metastasis of CSCs. Furthermore, we identify a putative mechanism by which SULF1 regulates interactions between CSCs and their microenvironment. The approaches …
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Determination of p53 role in cancer biology and therapy through interactome development and analysis
… genes; CCNB1, CCNB2 along with KIF14, PDGFRB and SULF1. These offer potential for further investigation that could be exploited for greater therapeutic efficacy in sarcomatoid, and CYP24A1, HIPK4 and PEG3 in biphasic p53 (+/+) malignant mesothelioma tumours. Drug profile analysis of deregulated …