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Showing 1 to 8 of 8 for “"Succinylation"”.
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Phosphoryl-Coenzyme A, an Intermediate in Enzymatic Succinylation of Dihydrolipoic Acid
Made available in DSpace on 2015-05-12T17:02:37Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 0025286.PDF: 2989149 bytes, checksum: 555c748895855dbf1e4be9b513ad4dbc (MD5) Previous issue date: 1957
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Modification of soybean proteins by immobilized proteases
… and foaming ability. The order in which succinylation and hydrolysis by immobilized enzymes were done, conferred on soybean proteins various functional properties. Evaluation of the molecular size of modified soybean proteins with sodium dodecyl sulfate (SDS) indicated that immobilized …
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A Study Of Novel Activities Of Type Iii Sirtuins: Cobb And Pfsir2A
… activity. The physiological importance of lysine succinylation and malonylation is strengthened by proteonomic studies that have identified succinylated and malonylated proteins. Many of those proteins are involved in metabolism and gene regulation suggesting that Sirt5 is important. Our aim was …
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Textural properties of coagulated milk products containing soy protein
… to increase negative charges (acetylation, succinylation and alkylation) or modified by bulky neutral reagents (N-ethylmaleimide, glycine methyl ester and carbodiimide) lowered the strength of milk coagulum more than did native soy protein, whereas, the opposite was true for soy proteins …
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Chemical and enzymatic modification of whey proteins
… improved the surface properties of the proteins. Succinylation, in particular, imparted a significant resistance against browning development upon storage in an intermediate moisture system. Enzymatic deamidation, via trypsin and chymotrypsin, resulted in proteins with improved solubility and …
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Investigating the role of ACSS2-mediated acetyl-CoA metabolism on EGFR-PI3K-PKB signalling
… of succinyl-CoA levels, and subsequent succinylation and mitochondrial function. Overall, the work in this dissertation has identified an important insight into off-target effects of a widely used ACSS2 inhibitor, VY-3-249, which should be carefully considered when used in the field. …
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TUMOR PROMOTING FUNCTIONS FOR THE METABOLIC REGULATOR SIRT5
… adenine dinucleotide-dependent demalonylation, desuccinylation and deglutarylation. SIRT5 impacts diverse metabolic pathways. One substrate of SIRT5 is carbamoyl phosphate synthase 1 (CPS1), an enzyme involved in the rate-limiting step of the urea cycle. By deacylating CPS1, SIRT5 promotes urea …
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Investigation into Tissue-Specific Mechanisms of Mitochondrial Dysfunction: Models of SUCLA2 Deficiency and a Screen for Potential Genetic Modifiers
With no currently effective treatments available, mitochondrial diseases are one of the most common forms of inherited multisystem disease. Primary disorders of the mitochondria affect an estimated 1 in 4,300 people with typical onset in early childhood. Mitochondrial disorders are classically …