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Showing 1 to 20 of 27 for “"Succinic Acid"”.
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The Synthesis of Succinic Acid and its Extraction From Fermentation Broth Using a Two-Phase Partitioning Bioreactor
Succinic Acid (SA) is an intermediate in the production of fine and commodity chemicals. No commercial SA bioproduction process exists due to process limitations including end product inhibition and high product separation costs, which account for 70% of total production costs. Two-Phase …
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Polymeric Chemisorbents for Organic Acid Recovery from Aqueous Solution
The high cost of recovering succinic acid (SA) from fermentation media during bioproduction makes it difficult for bioproduced SA to compete with petrochemically-derived SA. Two new polymeric sorbents and multiple recovery methods that have the potential to reduce bioproduction costs are examined. …
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The influence of succinic acid 2,2 dimethylhydrazide (Alar) on net CO₂ assimilation rate, chlorophyll content, anatomy, and morphology of vegetative growth of the apple, Malus sylvestris Mill
A 2 year study was conducted to investigate the influence of Atar on young apple trees. In 1996 concentrations of 0, 500, 1000, 2000, 4000, and 8000 ppm of Alar were applied to 'Golden Delicious', 'York Imperial' and 'Delicious' cultivars growing outside in gallon containers.
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Differential progression of pancreatic premalignancy in geographically distant murine transgenic cohorts uncovers key role of microbial metabolites
… These analyses identified an abundance of succinic acid in the plasma and pancreata of mice displaying the accelerated phenotype. We utilized an independent transgenic mouse model in which PDAC driver mutations are expressed pancreas-wide, which developed a wide array of pancreatic …
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Preliminary framework for quantitative sustainable design of redox-mediated electrodialysis for biorefinery separations
… help advance the production of bio-based organic acids, including succinic acid. Redox-ED is one particular class of electrochemical technology that can contain novel layer-by-layer (LBL) membranes and employ a modified cell pair and redox-flow platform. Environmental and chemical engineering …
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Feasibility for value addition to sucrose in South Africa through conversion to platform chemicals
… commodity chemicals such as surfactants, organic acids and polyols. It is therefore imperative to find sustainable ways of generating value added platform chemicals from sucrose. The quantitative and qualitative study of this project looks at determining the chemicals that should be considered as …
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Application of metabolic and biochemical engineering techniques to enhance metabolic flux throughput and improve succinate production in Escherichia coli
… The pathway leading to the production of succinic acid was examined for the effects of level of carbon substrate available to the system and overexpression of the phosphoenolpyruvate carboxylase (PEPC) enzyme system coupled with pathway manipulations and use of different carbon sources. …
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The Role of the Parotid Salivary Glands in the Regulation of Insulin Secretion
… (PH), sodium fluoride (NaF), or guanidino-succinic acid (GSA) were examined for effects on fasting plasma glucose and insulin or effects on intravenous glucose tolerance in male Sprague-Dawley rats. Basal glucose and insulin were substantially elevated as a result of the stress of …
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Metabolism, nutritional effects, and mutagenesis of crystal violet decolorization by a biofungicide agent Pseudomonas putida strain M-17
… of ammonia, nitrate or urea for the amino acid nitrogen source. However, a different medium containing succinic acid and using ammonia as the sole nitrogen source was found to induce the reaction. Factors that did not affect the decolorization reaction included temperature (14-30° C) and pH …
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Co-crystallisation of α,ω-dicarboxylic acids with nicotinamide and isonicotinamide
… formed. Selected α,ω-alkanedicarboxylic acids (HOOC-(CH\(_2\))\(_{n-}\)COOH) were crystallised with nicotinamide for n = 0, 1, 2, 4, 5, 6, 7 and isonicotinamide for n = 5, 6, 7 yielding 12 new solid materials. The melting point of the starting materials and new products are determined and …
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Organic acids bioproduction from corn fiber using Actinobacillus succinogenes
Succinic acid (SA) and lactic acid (LA) are organic acids which are used to synthesize high value industry chemicals, which have applications in the food, agricultural, chemical, and pharmaceutical industries. Currently, these acids are produced primarily from fossil-fuel feedstocks, which are …
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On the Effectiveness and Challenges of Electrosynthesis Strategies in Escherichia coli
… of Escherichia coli for the purpose of producing succinic acid. The results of this task showed wild-type cells exhibited the greatest molar increase in succinate yield with an 89% increase while an ldhA deficient strain showed 40% increase. The lack of direct charge transfer was implicated as the …
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Analysis of the Metabolism of Dextran-Methylprednisolone Succinate Using
… joined to a 70,000 Da dextran molecule through a succinic acid linker to form Dextran-methylprednisolone succinate @exMPS). A newly developed reversed-phase HPLC assay is validated, and is capable of simultaneous measurement of methylprednisolone (MP), methylprednisolone succinate (MPS), …
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Combining chemical with biological oxidation for efficient treatment of chloronitrobenzene in groundwater
… to form dicarboxylic products including muconic acid, succinic acid, malic acid, and maleic acid. Further electrochemical oxidation of these dicarboxylates was slower by about two orders of magnitude. To evaluate the universal biodegradability of the generated intermediates, the electrochemically …
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Catalytic conversion of biomass-derived molecules into mono- and dicarboxylic acids and esters
… of fuels and chemicals. Mono- and dicarboxylic acids and esters are key intermediates to chemical products, especially for biodegradable polymers. This thesis has addressed the challenges in chemocatalytic synthesis of mono- and dicarboxylic acids and esters, including gluconic acid, succinic …
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A Study of Polymer-Small Molecule Interactions for Solid-Liquid Two Phase Partitioning Bioreactors With Emphasis on the Bioproduction of 2-Phenylethanol
… 2-phenylethanol, cis-1,3-indandiol, iso-butanol, succinic acid and 3-hydroxybutyrolactone. Furthermore, the biotransformation from L-phenylalanine to 2-phenyethanol, an important aroma compound in industry, was examined in detail. It was found that relatively hydrophobic compounds tend to be …
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The nutritional characteristics and requirements of a butyrivibrio
… of its production of certain volatile fatty acids in a rumen fluid-glucose medium fermentation. The characteristic fermentation waa the production of a large amount of butyric acid and 1ome lactic acid or succinic acid, and the lack of production of propionic acid. It was found that when …
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Defining giftedness: an ethnographic approach
… of its production of certain volatile fatty acids in a rumen fluid-glucose medium fermentation. The characteristic fermentation waa the production of a large amount of butyric acid and some lactic acid or succinic acid, and the lack of production of propionic acid. It was found that when …
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