Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 44 for “"Structural MRI"”.
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The effects of HIV-1 infection on subcortical brain structures in children receiving ART : a structural MRI study
… structures as measured on high-resolution structural Magnetic Resonance Imaging (MRI) scans traced manually. The sample comprised 79 5-year old children, 52 with HIV and 27 uninfected controls. Infected children were all stable on antiretroviral therapy (ART) and were from the Children with …
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The longitudinal effects of HIV and ART on the developing brain: a structural MRI study using manual segmentation
… better understand contributing factors. Methods: MRI scans were obtained at ages 5, 7, and 9 years, on a 3 T Allegra MRI (Siemens, Erlangen, Germany), and 10 years 3 T Skyra Siemens. Images were manually traced, by the author, for volumes of basal ganglia structures and corpus callosum using …
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Efficient Moments-Based Permutation Tests: A Framework, Methods and Applications
… experiments and magnetic resonance imaging (MRI) brain data, including the multi-site voxel-based morphometry analysis from structural MRI (sMRI) and activation detection from functional MRI (fMRI).
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Magnetic Resonance Based Imaging for Degenerative Cervical Myelopathy
… cord compression using Magnetic Resonance [MRI] has therefore become a gold standard assessment for diagnosis and popular outcome assessment. This approach has limitations, which are poorly recognised in clinical care and research, representing a knowledge translation gap. Improving MRI …
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The Measure and Meaning of Structural Similarity in the Brain
… structure. At the same time, recent advances in structural MRI analytics have enabled large-scale mapping of anatomical similarity within individual brains. However, key questions remain that limit the current applicability and interpretability of research using similarity mapping approaches. …
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Factors Affecting Resting-State Functional Connectivity Across Three Intrinsically Connected Networks in Traumatic Brain Injury
… and intelligence estimates. They also underwent structural MRI, resting-state fMRI, and completed mood symptom questionnaires. A seed-based, resting-state functional connectivity analysis was conducted for the DMN, CEN, and SN. Measures of brain volumetrics were calculated from the structural …
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Hierarchical Bayesian Models for Multimodal Neuroimaging Data
… techniques for brain mapping. This wide range of structural and functional imaging modalities provides a major source of information-rich data which may be used to non-invasively understand the human brain, and is a promising source of information for improved clinical diagnosis and treatment …
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Investigating brain metabolite levels in adolescents living with HIV using atlas-based magnetic resonance spectroscopic imaging (MRSI)
… including a high-resolution T1- weighted structural MRI using a multi-echo magnetization-prepared rapid acquisition gradient echo (MEMPRAGE) sequence and volumetric MRSI using spiral-encoded localized adiabatic selective refocusing (LASER) CSI. LCModel was utilized to achieve spec
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Combining Computational Techniques with Physics for Applications in Accelerated MRI
Magnetic Resonance Imaging (MRI) non-invasively measures high-resolution images of soft tissue contrast in human anatomy without any ionizing radiation or injection of contrast agent. However, MRI incurs large costs to patients and researchers due to expensive equipment and slow imaging times. …
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The Neural Correlates of Allocentric Spatial Memory in Schizotypy
… Personality Questionnaire. Functional and structural MRI was used to investigate the neural correlates of allocentric spatial memory in schizotypal personality. Allocentric spatial memory is reported to be impaired in schizophrenia and this is thought to be related to alterations in …
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Evidence Of Distinctive Structural Alterations That Differentiate Adhd Boys With And Without A Comorbid Reading Disability
… However, the extents to which comorbid RD impact structural alteration in children with ADHD have never been investigated. The overall goal of this study was to assess structural alterations in the subcortical, cortical and white matter that may differentiate ADHD/-RD from ADHD/+RD. The general …
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Executive Functioning as a Mediator of Relations Between Neural Structure and General Psychopathology in Pre-Adolescents
… were utilized. Neural structure was captured via structural MRI scans at baseline, and EF was divided into inhibitory control (IC) and working memory (WM) tasks measured at two-year-follow-up. Psychopathology at three-year-follow-up was modeled using a bi-factor confirmatory factor model …
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Imaging Correlates of Heterogeneity in the Syndromes Associated with Frontotemporal Lobar Degeneration
… that a multi-modal imaging approach, including structural and task-free functional magnetic resonance imaging, will provide mechanistic insight into how phenotypic variance arises and improve predictions of disease progression and survival. In this thesis I draw from data for participants …
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Grey matter morphological changes in late life using magnetic resonance imaging technique
… into three broad topic areas. While a few structural MRI studies have examined the relationship between cognitive function and brain morphology using regions of interest methodology, whole brain analyses have been generally lacking. The first topic is to examine the voxel‐wise correlation …
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Evaluation of the pharmacokinetics, pharmacodynamics, and safety of enrofloxacin administration to pregnant mares
… long term effects of mild in utero toxicity. Structural MRI, qMRI and RT-PCR analysis failed to detect changes in cartilage properties in the in utero-exposed animals. Overall, it is proposed that enrofloxacin and its active metabolite ciprofloxacin cross the equine placenta and reach the …
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Recognizing Brain Regions in 2D Images from Brain Tissue
… anatomical structures are present in an image. Structural MRI provides a clear, high-resolution visualization of the anatomy of the brain, capturing physical characteristics like the size and shape of different regions of the brain or the presence of abnormalities such as tumors. Whereas sMRI …
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Exploring the relationship between multimodal magnetic resonance neuroimaging and cognitive outcomes in children: applying machine learning algorithms to brain MRI features to predict cognitive scores and performance categories of children living with and without HIV
… Magnetic resonance (MR) imaging (MRI) is a versatile tool that can be used to measure a broad range of brain tissue properties giving rise to cognitive functions. For example, structural MRI (sMRI) can quantify brain volumes and other morphometrics, diffusion tensor imaging (DTI) …
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Neuroimaging Investigation of Binge Alcohol Drinking and Opioid Dependency.
… of functional magnetic resonance imaging (fMRI) studies on substance use disorder and ii) an instrumental learning task with fMRI and spectroscopy which was used to study habitual binge alcohol drinkers using a Research Domain Criteria (RDoC) framework testing allostasis theory hypotheses. …
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Novel Random Forest Methods and Algorithms for Autism Spectrum Disorders Research
… multi-site (clustered data) using resting-state fMRI (rs-fMRI) and structural MRI (sMRI). These algorithms control the random effects of the confounding factor of the site and fixed-effect of phenotype variable of age internally while building the prediction model. On top of controlling the …
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Cognition and apathy in normal pressure hydrocephalus
… was associated with more severe apathy. A structural MRI study was then conducted to expand on these findings and to define brain structural correlates of apathy in NPH (Chapter 4). Results from this study suggested a potential role of the caudate nuclei in apathetic symptoms in NPH. …
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