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Showing 1 to 1 of 1 for “"Structural Biology, CryoEM"”.
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Integration of Structural Methods to Characterize the Dynamics of Macromolecular Complexes
… cryo-EM and x-ray crystallography. Using this structural information, we assess the energetics of DNA binding to the promoter binding pocket via molecular dynamics. Furthermore, energetic, and structural insights enable the design of a mutant RNAP holoenzyme which can recognize altered …