Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Stroke models"”.
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Effect of sinusoidal extremely low-frequency electromagnetic stimulation on neurons and glia in a transient stroke model
Ischemic stroke is one of the leading causes of death worldwide. Nowadays, treatment options despite their benefits, have limited use. Therefore, the search for new therapeutic strategies is imperative. Previous studies proved sinusoidal extremely low-frequency electromagnetic stimulation (ELF-EMS) …
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The development of a method to deliver neuroprotective peptides specifically into stroke-affected neurons
Stroke is a pathological condition that causes extensive brain damage. During ischemic stroke, an excess of the excitatory neurotransmitter glutamate exerts many deleterious effects, which leads to cellular damage and cell death, a phenomenon appropriately termed excitotoxicity. Among the events …
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Endoplasmic Reticulum Dynamic Structural Changes in Neurons: The Fission-Fusion Phenomena
… reported to be protective in experimental stroke models, enhances ER fragmentation. Finally, we validate the occurrence of rapid neuronal ER fission in an animal cardiac arrest model of cerebral ischemia. We assessed ER structure using confocal microscopy live cell and tissue imaging, …
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Towards a reproducible model for subcortical capsular strokes
Following stroke, survivors often experience long lasting upper limb motor impairments that can vary in severity. A prominent category of these upper limb deficits are caused by damage to the capsular region caused by ischemia in the anterior choroidal artery. However, animal research has focused …
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Functionalised self-assembled peptide hydrogel for cell transplantation
… and promote the cell integration in both animal models of Parkinson's disease (PD) and ischemic stroke. This thesis reports the rational design and functionalisation of fluorenylmethyloxycarbonyl-self-assembled peptide (Fmoc‐SAP) scaffolds for cell transplantation, demonstrating their ability to …
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Functionalised self-assembled peptide hydrogel for cell transplantation
… and promote the cell integration in both animal models of Parkinson's disease (PD) and ischemic stroke. This thesis reports the rational design and functionalisation of fluorenylmethyloxycarbonyl-self-assembled peptide (Fmoc‐SAP) scaffolds for cell transplantation, demonstrating their ability to …
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Modelling of risk factors, case-fatalities, survival and functional health status for stroke in Kelantan, Malaysia
Stroke is an important public health problem worldwide. It is a non-communicable disease of increasing importance in the ageing population. There are four major types of stroke: a) ischaemic stroke, b) primary intracerebral haemorrhage, c) subarachnoid haemorrhage and d) undetermined stroke (no …