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Showing 1 to 7 of 7 for “"Striatin"”.
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Role of Striatin Complexes in the Control of Development and Secondary Metabolism of the Filamentous Fungus Aspergillus nidulans
Striatin is a highly conserved eukaryotic protein first discovered in neuron cells of mammals. It is involved in many molecular processes, including cellular signaling, cell division and development. It has been shown in several fungi that striating complexes are important for development. Fungal …
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Regulation and communication between the NRD kinase COT1, the MAK2 MAP kinase and the Striatin complex in Neurospora crassa
… zwischen GC Kinasen, MAP Kinasen und dem Striatinkomplex beschrieben, welcher eine tragende Rolle bei der Endocytose, Signalweiterleitung und Zelladhäsion spielt. Das Striatinhomolog HAM3 in N. crassa und dessen Interaktionspartner MOB3 zeigen dieselben Entwicklungs- und …
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Structure-function Analysis of the STRIPAK Complex
… complex, which we termed STRIPAK (for STRiatin Interacting Phosphatase and Kinase). The STRIPAK complex contains a protein phosphatase 2A (PP2A) holoenzyme and a family of Ste20 kinases (the GCK-III kinases), as well as the protein MOB4, a member of the MOB family of proteins, which are …
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Untersuchung der Fruchtkörperentwicklung bei dem Hyphenpilz Sordaria macrospora
Die funktionelle Analyse von Proteinen der Striatin-Familie aus Säugern gewinnt immer mehr an Bedeutung, da diese vermutlich eine zentrale Rolle in Calcium-abhängigen Signaltransduktionsprozessen einnehmen, welche vielfältige zelluläre Differenzierungsprozesse regulieren. Striatin-Proteine dienen …
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IDENTIFICATION AND CHARACTERIZATIONS OF PATHOGENICITY GENES IN FUSARIUM VIRGULIFORME, THE CAUSAL AGENT OF SOYBEAN SUDDEN DEATH SYNDROME (SDS)
… protein kinase 1 ortholog), the Fvstr1 gene (a striatin protein ortholog) were functionally characterized through a gene knock-out strategy. Targeted disruption of the FvSNF1 locus in wild type F. virguliforme strain reduced virulence significantly on soybean and abolished galactose utilization. …
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MES-DERIVED CARDIOMYOCYTES AS CELLULAR MODEL TO STUDY CARDIAC DISEASES: ALTERATIONS IN STRN AND GNB5 GENES
Striatin (Strn), a scaffold protein expressed in many tissues, among which in cardiomyocytes (CMs), whose altered expression has been found in various cardiac diseases. Here we studied the role(s) of cardiac STRN by comparing the electrophysiological properties of CMs, generated from STRN-KO and …
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Understanding the role of dMob4 in postembryonic Neural Stem Cell mitotic reactivation
… 4 (Mob4), a member of the highly conserved Striatin-Interacting Phosphatase and Kinases (STRIPAK) complex, identified by our laboratory in a transcriptome analysis comparing quiescent and reactivating NBs. I show that Mob4 is upregulated in reactivating NBs, and its loss prevents NB …