Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Stress Response System"”.
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Cross-Pathway Control of the Pathogenic Fungus <i>Aspergillus fumigatus</i>: a Manifold Stress Response System
… dass der transkriptionelle Regulator CpcA dieses Systems Einfluss auf die Virulenz hat.Im ersten Teil dieser Arbeit wurden mittels Transkriptomanalyse der Wildtyp und eine cpcA-Deletionsmutante unter Aminosäuremangelbedingungen miteinander verglichen. Dabei wurden 377 Gene identifiziert, deren …
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Biology Through the Lens of Trauma: An Empirical Review of Trauma Treatments
… practice gap for the treatment of Post-Traumatic Stress Disorder (PTSD). Biological mechanisms of the stress response system are explored as they pertain to trauma and its subsequent effects on the brain and body. In addition, American Psychological Association (APA) recommended evidence-based …
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Extracytoplasmic stress response systems in S. Typhimurium
… disease from mild food-poisoning enteritis to a systemic, sometimes fatal typhoid infection. These bacteria have evolved to survive in different environments within and outside the host and do so through the regulation of differential gene expression following activation of certain stress …
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The role of the BHLH038 transcription factor in the regulation of osmotic and drought stress responses in Arabidopsis thaliana
The most important abiotic stress affecting agriculture worldwide is drought. In order to ensure food supply for the expanding world population two critical tasks must be undertaken; maintenance of crop yield as well as the increase of yield potential. Plants have built up a complex stress response …
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Relative contributions of the stringent response mediators (p)ppGpp and DksA to Haemophilus ducreyi virulence in humans
… infection, H. ducreyi is subject to a variety of stresses. The stringent response is a bacterial stress response system induced by nutrient limiting conditions and mediated by guanosine tetra- and pentaphosphate [(p)ppGpp] and the transcriptional regulator DksA. (p)ppGpp and DksA jointly interact …
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Traumatic Brain Injury As An Environmental Risk Factor For Neurodegeneration: Elucidating Causal Mechanisms With Drosophila
… and chaperone activity. An acute boost of the stress response system through increase of the transcriptional regulator heat shock factor, or through an environmental sub-acute heat stress alleviates the lifespan and brain degeneration deficits of the severe dTBI. Together, these results present …
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Effects of urbanization on the physiology, behavior, and fitness of a wild songbird
… urban birds' termination of the glucocorticoid stress response by looking at their ability to reduce circulating levels of glucocorticoid 'stress' hormones and the relative abundance of receptors that provide negative feedback in the hippocampus and hypothalamus. I found that urban males have a …
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LONG-LASTING MOLECULAR ALTERATIONS FOLLOWING EARLY LIFE STRESS IN RATS: ROLE OF GUT MICROBIOTA AND INFLAMMATION
It is well known that stress, especially when experienced early in life, affects the brain developmental trajectories leading to an enhanced vulnerability for several mental disorders later in life. The adverse outcomes depend on the timing of the stressful experiences, and in this contest, early …
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Molecular Mechanisms of Antimicrobial Resistance In Multi-Drug Resistant Enterococci
… to all existing antimicrobials. The LiaFSR system regulates resistance to cell membrane (CM) stressors like daptomycin (DAP), a front-line drug for multi-drug resistant infections. DAP resistance (DAP-R) in <em>E. faecalis </em>is mediated by CM phospholipid alterations. Emergence of DAP-R …