Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"Streptomyces albus"”.
-
Activación de rutas de biosíntesis silenciosas en Streptomyces albus J1074
… los actinomicetos, y en particular el género Streptomyces, entran dentro de esta categoría de potenciales productores de nuevas moléculas bioactivas. Streptomyces albus J1074 presenta en su genoma al menos 27 agrupamientos génicos para la biosíntesis de metabolitos secundarios potencialmente …
-
Biosynthesis of Fluorinated Natural Product Nucleocidin
… is a fluorinated adenosine analogue produced by Streptomyces calvus. It is one of only six known fluorinated natural products. The 4’-fluorine substituent on nucleocidin requires a unique two-step fluorination mechanism: C-H bond cleavage followed by stereospecific glycosylation of the fluoride …
-
Natural Products From Functional Screening of Soil Metagenomic Libraries
… screening: Ralstonia metallidurans and Streptomyces albus, and found that both are powerful hosts for finding a wide range of natural products. Functional screening of a 700,000 cosmid clone library in R. metallidurans for antibiotic activity led the discovery of a diverse set of …
-
Novel Molecules from Environmental DNA-Derived Type II Polyketide Biosynthetic Gene Clusters
… hurdle of rediscovering known metabolites. Streptomyces is a microbe that has been a particularly rich source of natural products; however, it has been predicted that the last easily accessible novel Streptomyces metabolite will be found within the next few years (Watve, Tickoo et al. 2001). …
-
Mining and Manipulation of Antibiotic Biosynthesis in Streptomyces
… agents remains the natural products produced by Streptomyces and allied bacteria. The advent of genome-level sequencing has changed how such bioactive products are identified in two ways: first, by enabling new approaches to engineering of known clusters to obtain new analogues; and secondly by …
-
Development and application of synthetic biology tools for natural product research
… Previously Zhao group discovered a PTM from Streptomyces griseus and characterized its biosynthesis, indicating a parallel biosynthetic mechanism. To further explore if this is general for the biosynthesis of all PTMs, I made four constructs which are supposed to make different intermediates …