Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Streptococcal toxic shock syndrome"”.
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Outcomes of Beta-Hemolytic Streptococcal Necrotizing Skin and Soft Tissue Infections and the Impact of Clindamycin Resistance
… may improve outcomes in patients with serious streptococcal infections. However, clindamycin resistance is growing worldwide, and resistance patterns in NSTI and their impact on outcomes are unknown. Methods: Between 2015 and 2018, NSTI patients at a quaternary referral center were followed for …
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Use of an Animal Model of Group A Streptococcal Infection to Identify Factors Important for Virulence
… necrotizing fasciitis (flesh eating disease) and streptococcal toxic shock syndrome (STSS). Virulence of the GAS is multifactorial, as it possesses an array of virulence factors regulated in a coordinated fashion by a complement of transcriptional regulators. A mouse model of streptococcal …
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Actions of Antimicrobial Peptides and Bacterial Components in Inflammation
… inflammatory response contributing to septic shock. LL-37 has been studied as an alternative to conventional antibiotics but clinical trials have been hampered by indications of its toxic effect on mammalian cells and evidence that its antimicrobial effects are inhibited by serum. It has been …
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Biochemical and Immunological Mechanisms Underlying Differential Interaction of Superantigens with Host Immunogenetic Factors in Streptococcal Sepsis
… array of diseases ranging from pharyngitis to streptococcal toxic shock (STSS), which is caused by excessive cytokines responses triggered by streptococcal superantigens (Strep SAgs). SAgs interact simultaneously with HLA class II molecules on antigen presenting cells (APC) and with the T cell …