Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"Stre"”.
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Robust Prediction of Large Spatio-Temporal Datasets
… ancestor, the Spatio-Temporal Random Effects (STRE) model. STRE is a statistical model with linear order complexity for processing large scale spatiotemporal data. However, STRE has been shown sensitive to outliers or anomaly observations. In our design, the St-RSTP model assumes that the …
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Efficient Algorithms for Mining Large Spatio-Temporal Data
… />version of the Spatio-Temporal Random Effects (STRE) model, namely<br />the Robust STRE (R-STRE) model. The regular STRE model is a recently<br />proposed statistical model for large spatio-temporal data that has a<br />linear order time complexity, but is not best suited for<br />non-Gaussian …
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Inflammatory response in maternal serum during preterm labour
… receptor expressed on myeloid cells-1 (sTRE M-1), matrix metalloproteinases (MMP)-9 and MMP-3, tissue inhibitor of metalloproteinases (TIMP)-1, TIMP-2, TIMP-3 and TIMP-4 and a panel of 30 cytokines, chemokines and growth factors. Our study showed that serum levels of sTRE M-1 were …
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Metagenomica applicata allo studio del microbioma delle piante
… di agrumi e olivo in diverse condizioni di stress biotico e abiotico. Inoltre, l'ambiente radicale delle piante di pomodoro è stato studiato anche lungo la catena di coltivazione di questa coltura, dal vivaio alla serra. Inoltre, è stato condotto uno studio per esaminare l'effetto di due …
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HOW TO REDUCE TRANSPLANT STRESS IN URBAN TREES
… post planting pruning can help reduce transplant stress and improve establishment, root development, and ecosystem service provision in young urban trees. It addresses four main questions: (i) whether substrate amendment with Ascophyllum nodosum extracts can accelerate nursery production and …
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INTEGRATED MOLECULAR INVESTIGATIONS OF MYRF AND SFRP2: UNVEILING REGULATORY MECHANISMS OF ER STRESS AND ECM REMODELLING IN PANCREATIC CANCER
… of ER activity. Considering the impact of ER stress on cancer cell fitness and drug-induced toxicity, the possibility to influence ER regulation by modulating MYRF trimerization and cleavage by targeting UGGT1 may provide therapeutic opportunities; ii) a better characterization of SFRP2 and …
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MOLECULAR MECHANISMS ORCHESTRATING LYSOSOME-MEDIATED DEGRADATION OF RIBOSOMES IN ANEUPLOID CELLS
… cell physiology, causing a plethora of cellular stresses. One of the most prominent effects of abnormal karyotypes is the development of proteotoxic stress, which is characterised by the aggregation of aberrant proteins in the cytoplasm. The disruption of protein homeostasis correlates with and …
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Pharmacotherapy for Social Anxiety Disorder and Posttraumatic Stress Disorder: New Meta-Analytic Approaches to Synthesising the Evidence
… Social anxiety disorder (SAD) and posttraumatic stress disorder (PTSD) are prevalent, disabling and highly comorbid disorders. SAD is the most prevalent of the anxiety disorders, and PTSD is the central disorder in the DSM-5 section on trauma- and stressor-related disorders. Given the growing …
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FROM SUSCEPTIBILITY TO RESILIENCE: Exploring sex-specific responses to mild and severe stressful events [DALLA SUSCETTIBILITA' ALLA RESILIENZA: Analisi delle risposte sesso-specifiche ad eventi stressanti di intensità moderata e severa]
Lo stress è una componente inevitabile della vita quotidiana, ma le persone lo percepiscono e lo affrontano in modi diversi, con conseguenze variabili sulla salute. Sebbene le risposte allo stress siano essenziali per la sopravvivenza, negli ultimi anni si è assistito a un aumento dei disturbi ad …
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UNDERSTANDING THE MOLECULAR MECHANISM LINKING ATM TO METABOLIC REGULATION.
… a role for ATM in cellular metabolism, oxidative stress response and insulin signaling. However, it is unclear how defective ATM-dependent response to oxidative stress contributes to A-T clinical manifestations. Here we show that ATM activates glycolysis upon oxidative stress and that its loss …
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MOLECULAR DISSECTION OF THE CROSSTALK BETWEEN ONCOGENIC AND TUMOR SUPPRESSIVE PATHWAYS: THE CASE OF TAZ-BRCA1 AND MYC-SETX GENETIC INTERACTIONS
… conflicts and enhanced replication stress to cytotoxic levels, thus triggering accumulation of DNA damage and cell death in cells challenged with oncogenic levels of Myc. Therefore, we unveiled a novel vulnerability of Myc-overexpressing cells, which require to coordinate …
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Exploitation of morphometric, biochemical and genetic traits of traditional vegetable for providing novel foods [Valutazione dei tratti morfometrici, biochimici e genetici di ortive tradizionali per la produzione di novel foods]
… da orto, selezionando genotipi resilienti agli stress abiotici, come siccità e ridotta radiazione luminosa, anche attraverso l’utilizzo di biostimolanti. Particolare attenzione è stata rivolta alla famiglia botanica delle Brassicaceae, con un focus specifico su Brassica oleracea L., nota per …
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CLINICAL AND BIOLOGICAL FACTORS OF MATERNAL DEPRESSION IN PREGNANCY AND RISK OF AN ALTERED NEURODEVELOPMENT IN THE OFFSPRING: CLINICAL AND PRECLINICAL DATA
… che la depressione e l’esposizione allo stress durante la gravidanza possono avere sul neurosviluppo del feto, abbiamo voluto investigare quali siano i meccanismi coinvolti nella trasmissione intergenerazionale da madre a figlio del rischio di problemi della salute mentale. Per fare ciò, …
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CLINICAL APPLICATIONS OF PARAOXONASE-1 IN DOMESTIC ANIMALS: BEYOND CONVENTIONAL INFLAMMATORY MARKERS
Inflammation and oxidative stress frequently occur in domestic animals. The diagnosis and monitoring of inflammatory and oxidative conditions are based on markers that are so far considered accurate but may lack specificity and prognostic utility. In the last years’ research, interest has grown …
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Modulazione dell'eme ossigenasi nella Ferroptosi come nuova strategia antitumorale
… il ruolo dell'omeostasi del ferro e dello stress ossidativo nella progressione del carcinoma mammario. Concentrandosi sul processo di recente scoperta della ferroptosi, una forma di morte cellulare dipendente dal ferro, questo lavoro mira a identificare nuovi candidati farmacologici in …
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Role of PACAP-ADNP axis in neurodegenerative process
… Tuttavia, è stato ipotizzato che lo stress ossidativo (OS) giochi un ruolo cruciale nella degenerazione dei motoneuroni. Inoltre, è stato descritto che la mutazione SOD1 interferisce con l’espressione del fattore nucleare legato all'eritroide 2-correlato al fattore 2 (Nrf2), un …
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THE IMPACT OF REPLICATION STRESS ON THE EPIGENOME OF MOUSE EMBRYONIC STEM CELLS
… of DNA replication, known as replication stress, can expand the cell fate of mouse embryonic stem cells (mESCs) by activating totipotency and extra-embryonic pathways. However, the underlying epigenetic mechanisms remain unclear. Preliminary data indicated that polycomb repressive complex …
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Stress and Mental Workload Monitoring in Pilots Using a Physiological Signals Approach
L'abstract è presente nell'allegato / the abstract is in the attachment
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Wearable Solutions for Acute Mental Stress Assessment and Mitigation
L'abstract è presente nell'allegato / the abstract is in the attachment
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ZSCAN4 AND REPLICATION STRESS: SAFEGUARDING GENOME STABILITY IN MOUSE EMBRYONIC STEM CELLS
… leading to a condition known as replication stress (RS). RS slows down and eventually stalls replication forks. If stalled forks are not resolved, they can give rise to DNA double-strand breaks, thereby promoting genomic instability—a hallmark of cancer. Our laboratory discovered that …
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