Global ETD Search
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Showing 1 to 3 of 3 for “"Strand displacement reaction"”.
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Optimizing the Toehold-Mediated Strand Displacement Reaction on the Nanoparticle Surface by Altering the Surface DNA Density for the Design of a microRNA NanoOptical Sensor
… we examine factors influencing the toehold strand-displacement reaction on nanoparticle surfaces. Gold nanoparticles were functionalized with oligonucleotide sequences with varying surface density by incorporating diluent DNA strands. The hybridization of DNA yields aggregates which then …
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Scaling up Genetic Circuits in Mammalian Cells: A U1-snRNA-based Platform Enables Mammalian Cells to Compute the Bitwise Inversion of the Square Root of a Number
… nuclear RNAs by the use of the toehold-mediated strand displacement reaction. The transactivated miRNA also does not use any transcriptional regulators or exogenous proteins and, like the miRNA-based NOT gate, has a DNA footprint small enough to fit in a AAV virus.