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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"Stimuli Responsive Polymers"”.
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Targeted and stimuli-responsive polymers as chemotherapeutic delivery systems
… window can be increased through targeted, stimuli-responsive delivery, which increases the drug concentration at the diseased site, and releases or activates the drug only when it reaches the target. Cancer is a highly variable disease occurring in many organs. There is a need for delivery …
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Design and Synthesis of Stimuli-Responsive Polymers with Programmable Cleavability
Polymers comprise a large portion of modern-day materials, from everyday plastics that we can hold and use, to nanomaterials imperceptible to the naked eye. Applying synthetic chemistry to impart structural changes to established polymers offers a promising path to introduce novel functionalities …
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Adsorption/Desorption Process of Stimuli-Responsive Polymers on Simulated Natural Surfaces Using QCM-D & AFM Analysis
<p>The stimuli-responsive adsorption of polyelectrolytes to biosurfaces provides an important vehicle for development of protective coatings, delivery of therapeutic agents, and cosmetic applications. Developing a fundamental understanding of the mechanisms and kinetics of adsorption/desorption …
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Development of Novel Thermosensitive Polymers for Bioresponsive Drug Delivery
Stimuli-responsive polymers have already shotremendous promise in controlled and self-regulated drug delivery. Successful construction of responsive polymers requires amalgamation of chemical, physical and biological principles. For careful therapy, a great deal of advantages offered by …
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REDOX-RESPONSIVE POLYMER DELIVERY SYSTEMS FOR ANTI-CANCER DRUG AND IMAGING
… of safe and efficient delivery systems, stimuli-responsive polymers which undergo significant physical or chemical properties change in response to environmental variations are becoming more important. Exploring the much more reductive environment in intracellular compartments compared to …
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Designing Polymer Hydrogels for Extrusion-Based Additive Manufacturing
… of AM technologies and materials chemistry are stimuli-responsive polymers, which change their chemical and physical properties in response to specific environmental cues. Stimuli-responsive polymer hydrogels, in particular, are seeing significant interest in extrusion-based AM for the …
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Assessment of the biocompatibility, stability, and suitability of novel thermoresponsive films for the rapid generation of cellular constructs
Stimuli responsive polymers (SRP) are of great interest in the bioengineering community due to their use in applications such as drug delivery and tissue engineering. One example of an SRP is poly(N-isopropyl acrylamide) or pNIPAM. This SRP has the capability of changing its conformation with a …
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Synthesis and characterization of tethered poly(n-isopropylacrylamide) for quantitative cell adhesion studies
Environmentally responsive (or smart') polymers represent a new approach for controlling biofouling release. Poly(N-isopropylacrylamide) (PNIPAAm) is a thermo responsive polymer that can potentially be used to control biofouling, as it exhibits a change in its relative hydrophobicity above and …
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Thermoresponsive Glycopolymers via Controlled Radical Polymerization (RAFT) for Biomolecular Recognition
Stimuli responsive polymers (SRP) have attracted a lot of attention, due to their potential and promising applications in many fields, as protein-ligand recognition, on-off switches for modulated drug delivery or artificial organs. Poly(N-isopropylacrylamide) (PNIPAM) is one of the most widely …
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Functional and responsive surfaces via initiated chemical vapor deposition (iCVD)
Stimuli-responsive polymers provide a method to control system behavior through the use of an external stimulus, such as temperature, pH, or electric fields among others. Temperature-responsive polymers, especially those based on N-isopropylacryalmide (NIPAAm), are of particular research interest …
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Advancing the field of polypeptoids through the synthesis of novel architectures and thermoresponsive polymers
Peptidomimetic polymers are an emerging class of polymers that are structurally related to polypeptides. Due to their structural similarities, these polymers can be used to study some of the physical aspects of polypeptides (for example, protein folding). They are also increasingly being used in …
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Hybrid organic-inorganic nanomaterials for applications at the biointerfaces
… oxide nanosheets tailored at the surface with stimuli-responsive polymers (polyacrylate and/or polyacrylamide) or specific chemical functionalities (amine functionalisation, sulphur functionalisation). As to the biomolecular counterpart, the performed study involved proteins (ferritin and …
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PH-responsive polymeric materials for encapsulation and triggered release
… To address these challenges, scientists look to stimuli-responsive polymers as a solution because polymers can be designed with tailored properties thanks to advancement in polymer chemistry and engineering. This dissertation discloses a collaborative effort between the Zimmerman group and Dow …
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Investigating the Modification of Spontaneous Emission using Layer-by-Layer Self-Assembly
… on fabrication conditions, the spacer layer is stimuli responsive and its thickness can be dynamically tuned. This thesis contains three interlinked components. First, we vary LbL spacer layer thickness and explore the change in fluorescence lifetime induced by the modified photonic density of …
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Multilayer capsules with stimuli-sensitive properties : pH-response and carbohydrate-sensing
Polyelectrolyte microcapsules containing stimuli-responsive polymers have potential applications in the fields of sensors or actuators, stimulable microcontainers and controlled drug delivery. Such capsules were prepared, with the focus on pH-sensitivity and carbohydrate-sensing. First, …
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Thermal conductivity switching of polymers and lithium-ion battery electrode materials in response to external stimuli
… thermal conductivity of materials using external stimuli, many have failed to show a high and fast thermal property switching of material. In this dissertation, I present novel stimuli-responsive polymers and Li-ion battery electrode materials that involve a wide range of thermal conductivity …
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Self assembled transmembrane protein polymer conjugates for the generation of nano thin membranes and micro compartments
This project was focused on generating ultra thin stimuli responsive membranes with an embedded transmembrane protein to act as the pore. The membranes were formed by crosslinking of transmembrane protein polymer conjugates. The conjugates were self assembled on air water interface and the polymer …
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New hydrogel forming thermo-responsive block copolymers of increasing structural complexity
… describes the synthesis and characterization of stimuli-responsive polymers made by reversible addition-fragmentation chain transfer (RAFT) polymerization and the investigation of their self-assembly into “smart” hydrogels. In particular the hydrogels were designed to swell at low temperature and …
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