Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 28 for “"Stimulation parameters"”.
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Electric stimulation parameters for an epi-retinal prosthesis
… obstacle to the success of this approach. Stimulation of ganglion cell axons-which lie in the optic nerve fiber layer between stimulating electrodes and their intended targets, and which originate from a relatively diffuse peripheral region-would probably convey the perception of a …
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Intrinsic Optical Imaging of Cortex During Deep Brain Stimulation: Parameters, Spatiotemporal Dynamics and Neurovascular Coupling
Deep brain stimulation (DBS) is clinically used to treat various movement disorders and has a potential to ameliorate other conditions such as depression, epilepsy etc. However, the mechanism through which DBS alleviates symptoms is not clear which prevents its efficient application and expansion …
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Regulation of Circadian Rhythms by Sleep -Wake Centers in the Brainstem and Basal Forebrain
… and a microdialysis cannula aimed at the SCN. Stimulation of the LDTg or PPTg significantly increased acetylcholine (ACh) levels at the SCN. Circadian behavior measurements demonstrated that stimulation of the LDTg, PPTg or NBM during the early night significantly delayed circadian rhythms, …
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Study of the Effect of Fracture Completion Variables on Decline Curve Parameters for Long-Term Production Forecast of Shale Liquids
… from these reservoirs based on the fracture stimulation parameters and reservoir properties has led to a better understanding of the duration of important flow regimes and parameters used in production forecasting models. The decline curve analysis considered in the study is a combination of …
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Neurotransmitter and Neuromodulator Analysis Using Capillary Electrophoresis With Laser -Induced Fluorescence Detection
… brain of freely moving rats appears dependent on stimulation parameters, causing differential regulation of the circadian systems.
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Towards Closed-Loop Deep Brain Stimulation: Behavior Recognition from Human STN
<p>Deep brain stimulation (DBS) provides significant therapeutic benefit for movement disorders such as Parkinson’s disease (PD). Current DBS devices lack real-time feedback (thus are open loop) and stimulation parameters are adjusted during scheduled visits with a clinician. A closed-loop DBS …
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Opto-mechanical control of nerve growth
… neurotrophic factors, topography, and electrical stimulation have been proposed to enhance nerve growth. This thesis explores optogenetic neural stimulation as a means to control neurite growth that promises greater cell-type specificity than commonly used electrical stimulation. Using dorsal root …
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Binaural interactions in the auditory midbrain with bilateral electric stimulation of the cochlea
… auditory midbrain, were studied using electric stimulation of bilaterally implanted intracochlear electrode arrays. Neural tuning to interaural timing difference (ITD) was emphasized since it is an important binaural cue and is well represented in IC neural responses. Stimulation parameters were …
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Alternating Current Stimulation for Essential Tremor
… and transcutaneous alternating current stimulation on tremor in essential tremor, when delivered over the primary motor cortex and arm at a patient’s dominant tremor frequency. Our results revealed that both transcranial and transcutaneous open-loop alternating current stimulation, …
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Engineering and acute physiological testing of a retinal neurostimulator
Electrical stimulation of retinal neurons is known to elicit visual sensations. When applied to the retina in a spatial pattern, electrical stimulation may be capable of providing rudimentary patterned vision that may be of benefit to sufferers of degenerative retinal disorders. No such device has …
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Muscle Recruitment Mechanism under Optogenetic Neuromodulation
… overall quality of life. Functional electrical stimulation (FES) is the most commonly used technology to restore motion. Although FES is used extensively in the clinic, several drawbacks limit its application for long-term use. FES recruits larger motor units before smaller ones, causing muscles …
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Assessment and modulation of essential tremor using peripheral-nerve stimulation
… such as medications and thalamic deep brain stimulation, have not been adopted broadly because of the invasiveness of the treatments and their lack of efficacy. To address these limitations, the objectives of this PhD dissertation are (1) to quantitatively assess tremor movement, and (2) to …
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Invasive and Noninvasive Brain Stimulation Strategies for the Treatment of Tinnitus
… ascending auditory system. Further, by combining stimulation of auditory cortex with an irrelevant acoustic stimulus, we were able to suppress neural firing throughout the inferior colliculus, revealing at least one potential mechanism for gating relevant versus irrelevant sound inputs. Targeting …
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A study of pupil response components in human vision
… pupil response to periodic modulation of several stimulation parameters such as: luminance contrast, stimulus size, spatial and temporal frequency content, and colour. Much larger responses were found for square-wave as compared to sinusoidal luminance modulation. A model with two populations of …
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A study of pupil response components in human vision
… pupil response to periodic modulation of several stimulation parameters such as: luminance contrast, stimulus size, spatial and temporal frequency content, and colour. Much larger responses were found for square-wave as compared to sinusoidal luminance modulation. A model with two populations of …
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Computation and Numerics in Neurostimulation
Neurostimulation continues to demonstrate tremendous success as an intervention for neurodegenerative diseases, including Parkinson's disease, in addition to a range of other neurological and psychiatric disorders. In an effort to enhance the medical efficacy and comprehension of this form of brain …
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Functional electrical stimulation (FES) leg cycling exercise in paraplegia: a pilot study for the definition and assessment of exercise testing protocols and efficacy of exercise
… the effect on cycling performance of changes in stimulation parameters, and which might therefore be used to optimise them, were also investigated. Thus, a second aim of this work was to determine whether oxygen uptake and a new measure of stimulation cost (i.e. the total rate of stimulation …
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Use of Bioheat Modeling to Characterize and Optimize Implantable Medical Devices and Neuromodulation Technologies
… is widely adopted as a powerful tool to predict stimulation/recording parameter optimization, rapid electrode/device prototyping, investigating novel mechanism of action, and testing working principles of any medical devices. Many implantable neuromodulation technologies including Spinal Cord …
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Understanding the biomechanics of standing-up and sitting-down
Functional Neuromuscular Stimulation (FNS) has been shown to be effective in restoring certain upper and lower limb movements of spinal cord injured patients. The successful application of FNS to achieve standing-up and sitting-down, in persons with lower limb paralysis, depends largely on two …
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ETHANOL INHIBITION OF DOPAMINE TRANSMISSION IN ANIMAL MODELS OF ALCOHOL ABUSE LIABILITY
… between these voltammetry studies are the stimulation paradigms used for evoking dopamine release, which may represent two functionally different modes of firing for dopaminergic neurons. High frequency dopamine stimulations (>14 Hz) are used to model rapid `phasic' firing of dopamine …
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