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Showing 1 to 18 of 18 for “"Stilbenes"”.
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Sterically Crowded Copolymers Based on Functionalized Stilbenes
… crowded polyelectrolytes based on functionalized stilbenes with maleic anhydride or functionalized N-phenylmaleimides were prepared via a "protected" precursor polymer strategy. The polyelectrolyte precursors readily dissolved in organic solvents and were characterized by 1H NMR, SEC, TGA, and …
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Studies Related to the Alternating Copolymerization of Substituted Stilbenes
… A novel series of methyl substituted stilbenes were synthesized and copolymerized with maleic anhydride. A conversion-time study was undertaken to understand the methyl substituent effect on copolymerization rates. Methyl substituted stilbene-maleic anhydride copolymer compositions …
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Synthesis and evaluation of tetramethoxy stilbenes related to combretastatin A-4 as potential anticancer agents
… possible.The cytotoxicities of the synthesized stilbenes against two human cancer cell lines were obtained using an MTT assay. Not much testing has been done with modifications to the trimethoxy motif of CA-4 (Bukhari, Kumar, Revankar & Qin, 2017). In this project it was found in all cases, …
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Synthesis and Polymerization of Substituted Stilbenes with Maleic Anhydride for Membrane Solubilization and Protein Extraction
… Additionally, unsymmetrical dimethyl-substituted stilbenes and monosubstituted stilbenes ((E)-4-tert-butylstilbene, (E)-4-methoxystilbene, (E)-2-methoxystilbene, methyl (E)-4-carboxylatestilbene, and (E)-4-trifluoromethylstilbene) copolymerize with maleic anhydride without gelation. Rates of …
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Effetti del chitosano su composti polifenolici in colture cellulari di vite: aspetti molecolari e metabolici
Polyphenols, including flavonoids and stilbenes, are an essential part of human diet and constitute one of the most abundant and ubiquitous group of plant secondary metabolites. The level of these compounds is inducible by stress or fungal attack, so attempts are being made to identify likely …
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Synthesis and evaluation of novel antivascular agents for two-photon activation
… trials for cancer therapy. Combretastatins are stilbenes isolated from the African shrub Combretum caffrum. These agents interact with tubulin in a similar way to colchicine, causing destruction of blood vessels within tumours by binding to tubulin dimers and inhibiting angiogenesis in …
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ΣΥΝΘΕΣΗ ΚΑΙ ΧΗΜΕΙΟΦΩΤΑΥΓΕΙΑ ΔΙΥΠΟΚΑΤΕΣΤΗΜΕΝΩΝ ΣΤΙΛΒΕΝΙΩΝ
… OF A SERIES OF E-2-HYDROXY-4'-SUBSTITUTED STILBENES WAS ACCOMPLISHED IN GOOD YIELDS BY THE WITTIG CARBONYL OLEFINATION REACTION. THE OZONOLYSIS OF THESE STILBENOLS WAS FOUND TO BE CHEMILUMINESCENT, THE QUANTUM YIELDS (1,2X10-4 - 8,1X10-6) DEPENDING ON HAMMETT'S "6" CONSTANT FOR THE 4'- …
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Isolation and Structure Elucidation of Cytotoxic Natural Products from the Rainforests of Madagascar and Suriname
… Macaranga alnifolia yielded four new prenylated stilbenes, one new geranylated dihydroflavanol, and five known compounds. The stilbenoids are highly cytotoxic, and the National Cancer Institute (NCI) further evaluated one of the new compounds. Bark and leaf extracts from Cerbera manghas yielded a …
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Isolation and Structural Elucidation of Compounds from Natural Products
… of three compounds which were characterized as stilbenes. Their structures were elucidated by using 1D NMR and 2D NMR spectra and mass spectroscopic data.
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Linear Conjugated Molecular Wires: Organic Materials and Single-Molecule Electronics
… and employ our oligoene model compounds, the stilbenes, to differentiate the mechanical from electrical properties in molecular junctions. This enabled the development of new tools for uncovering the transport mechanisms in other molecules. One example is demonstrated in chapter 4, where …
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Synthesis and Solution Properties of Semi-rigid Polyelectrolytes and Polyampholytes
The incorporation of substituted stilbenes in copolymers affects the resulting solution properties and their controlled radical polymerizations. Substituted stilbene monomers readily polymerize in an alternating fashion with acceptor comonomers such as maleic anhydride and maleimide. These …
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The synthesis, structural characterization and biological evaluation of potential chemotherapeutic agents
… effects. The synthesis of fluorinated stilbenes containing the 3,5,4'-substituted backbone was accomplished. The compounds were synthesised via the Wittig reaction and the decarbonylative Heck reaction. In conjunction with fluorine, nitrogen was also used as a replacement for the oxygen …
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Aplicación foliar en el viñedo de un extracto del alga Ascophyllum nodosum como herramienta para mejorar la composición nitrogenada, fenólica y aromática de la uva y del vino de las variedades Tempranillo y Tempranillo Blanco
… the content in the trans-piceid and total stilbenes in grapes in both seasons. The treatments barely affected the content of phenolic compounds in grapes in 2018 season, however, the high dosage of the seaweed extract increased the content in musts of 6 several individual terpenes, C13 …
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Functional Nanomaterials From Bis-Urea Macrocycles
… such as coumarin and its methylated derivatives, stilbenes, acenaphthylene and styrenes. We developed the method to introduce these solid guests into the channel from its solution. We characterized the tubular host as well as different host*guest complexes by solid-state techniques including PXRD, …
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Inhibitors of tubulin, nitric oxide synthase, and HIF-1 alpha; synthesis, biological, and biochemical evaluation.
… 15 was the most effective of the fluoro-nitro stilbenes synthesized, having a tubulin IC50 of 2.9 µM, and a cell cytotoxicity of 0.0093 µg/mL against NCI H460 lung cancer carcinoma. Though VDAs have been effective against a variety of tumor cells, there are cancers, such as human oral squamous …
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Characterization, Interaction and Chemoprevention of Potent Constituents From Grape Cell Culture
… cell culture extracts are rich in flavonoids and stilbenes that are biologically active. The objectives of this study were (1) to evaluate catalytic inhibition of grape (a Vitis hybrid 'Bailey Alicant A') cell culture extract and subfractions on human DNA topoisomerase II for cancer …
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In search of human cytochrome P450 1A1 enzyme inhibitor
… products such as flavonoids, chalcones and stilbenes have attracted a great deal of attention since these compounds have an ability to modulate the activity of CYPs by inhibiting CYP-specific enzymatic activity. Several compounds have been found which potently inhibit CYP1 family of enzymes. …
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Selección de levaduras no-Saccharomyces para la elaboración de vinos tintos de calidad
… effect on the composition of anthocyanins and stilbenes of the wines sequentially fermented with non-Saccharomyces/S. cerevisiae. The implantation controls of the inoculated non-Saccharomyces yeasts showed that T. delbrueckii and L. thermotolerans strains and the mixed inocula constituted by …