Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Sti1"”.
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Characterizing Multivalent Interactions Between Folded Protein Domains and Intrinsically Disordered Regions or Peptide Substrates
… to be relatively strong and involves the STI1-I, linkers, and the C-terminal LLPS-mediating regions of UBQLN2. In contrast, the LLPS-enhancing UBA-IDR interaction is much weaker and involves mainly a middle linker and the C-terminal regions of the IDR after the STI1-II. Our results support …
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Protein misfolding toxicity and inclusion formation in cellular models of neurodegeneration
Protein misfolding characterizes most neurodegenerative diseases. Protein misfolding is the conversion of specific proteins from their normal, often soluble, and native three-dimensional conformation into an aberrant, often insoluble, non-functional conformation. Protein inclusions and aggregates …