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Showing 1 to 1 of 1 for “"Stess sensing"”.
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Regulation of mammalian IRE1α: Co-chaperones and their importance
… the luminal Hsp70 BiP and the luminal stress-sensing domain of IRE1α (IRE1LD). This is then built on by a series of in vitro experiments showing that ERdj4 catalyses formation of a repressive BiP-IRE1LD complex and that this complex can be disrupted by the presence of competing unfolded …