Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Steroid Receptor Coactivator-1"”.
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A Novel Phytoestrogen that Acts as an Agonist for Human Estrogen Receptors.
Estrogen is the natural agonist of the estrogen receptor (ER). However, certain plant-derived compounds or phytoestrogens have been identified that mimic estrogens and act as agonists and/or antagonists of ERs, depending on subtype and target tissue. Understanding how phytoestrogens interact with …
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Small Angle X-ray Scattering study of conformational changes in steroid responsive activator (SRA) RNA upon binding with suppressor protein SHARP
… and proliferation are known to be influenced by steroid stimulation. The steroid receptor activator (SRA) RNA is a large RNA transcript indicated to be an epigenetic regulatory component in the steroid receptor coactivator-1 (SRC-1) acetyltransferase complex. It is<strong> </strong>needed for a …
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Detailed Analysis of Transcriptional Regulation by Activation Functions-1 and -2 of the Human Estrogen Receptor
The human estrogen receptor (ER), is a 66 kilodalton, ligand-inducible transcription factor that regulates the transcription of estrogen-responsive genes. Like other steroid hormone receptors, the ER is a modular protein that can be divided into separable domains with specific functions, such as …