Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Stem Cell Plasticity"”.
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Molecular mechanisms of neural stem cell plasticity and neuro-regeneration in an Alzheimer’s-like neurodegeneration model of adult zebrafish
… proliferative and neurogenic ability of neural stem cells (NSCs), which normally produce neurons, albeit rather a limited lineage. Recently, in AD patients, neurogenic outcome was shown to reduce dramatically (Moreno-Jimenez et al., 2019; Tobin et al., 2019). This lack of neurogenic input from …
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Metabolic Coordination of Stem Cell Fate Controls Tumor Initiation and Tissue Repair
<p>Tissue stem cells balance fate decisions of self-renewal and differentiation to maintain homeostasis over the lifetime of an organism, as well as to repair tissues upon injury and wounding. Disrupting the balance between self-renewal and differentiation results in pathology: excessive …
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Untersuchung humaner Stammzellen aus dem adulten Knochenmark und der fetalen Leber
… ist das am häufigsten verwendete Modellsystem zur Untersuchung humaner Stammzellen in vivo. Die Schwächung des Immunsystems dieser Mäuse, welche auf einem Mangel an reifen B- und T-Zellen beruht, macht sie für transplantierbare humane Stammzellen empfänglich. Eine der verbliebenen …
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Lgr5 Regulation of Stat3 Signaling and Drug Resistance In Colorectal Cancer
… treatment and progression to metastasis. Cancer stem cells (CSCs) are believed to drive relapse because of their capacity to self-renew, acquire resistance mechanisms, and differentiate promoting tumor growth and heterogeneity. Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5), …