Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Stealth Liposomes"”.
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Turning stealth liposomes into cationic liposomes for anticancer drug delivery
… reported passive tumor targeting by PEGylated liposomes (stealth liposomes) have resulted in their higher tumor accumulation. However their interaction with cancer cells has been minimal due to the steric hindrance of the PEG coating. This dissertation reports two approaches to enhance the …
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Exploring Critical Vehicle Parameters for the Design of Multitargeted Nanoparticles for Cancer Specific Gene Delivery
… which can cause harmful side effects. The stealth liposomes has greatly improved tumor localization of small molecule drugs and is a promising tool for nucleic acid delivery as the polyethylene glycol coating its surface protects against immune recognition and blood clearance. In this …
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Nanocarriers for drug targeting and improved bioavailability
… of the first topic was the development of liposomes to which anti-TfR-monoclonal antibodies (Ox26) or lactoferrin was bounded to transport the selective NK3 receptor agonist senktide to CNS across the BBB. NK3 receptors are widely expressed in the CNS and their stimulation by senktide (ICV) …
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PEGylierte Sterole zur Funktionalisierung liposomaler Oberflächen
Die Entwicklung intelligenter Arnzeistoffträgersysteme, die in der Lage sind Wirkstoffe gezielt an den Wirkort zu transportieren, soll zu effizienteren und verträglicheren Therapieformen führen. Eine Möglichkeit, diesem Ziel näher zu kommen, stellt die Oberflächenmodifikation liposomaler …
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Nanosized systems for efficient delivery of antitumoral and anti-inflammatory drugs
… was to study two different nanosized systems, liposomes and nanosuspensions. Liposomes were develop with the aim to improve the Triiodothyronine (T3) delivery to hepatic cancer cells and nanosuspensions were proposed to enhance dermal bioavailability of Diclofenac acid, a potent nonsteroidal …