Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Staphylococcus aureus infections"”.
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IgG subclasses, specific antibodies and immunoglobulin allotypes in children with invasive Haemophilus influenzae type B and Staphylococcus aureus infections
… aspects of immunity in children with invasive infections due to Haemophilus influenzae type b and Staphylococcus aureus. These serious infections are a significant cause of childhood morbidity and mortality in all populations and affect healthy as well as compromised children. Evidence suggests …
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Synthesis and Design of ClpP Activators as Novel Antibiotics
… Design and synthesize novel compounds to treat Staphylococcus aureus infections by targeting the dysregulation of the Casein Protease P, ClpP. Methods. Utilize established chemical methods to synthesize ureadepsipeptides, small-molecule ClpP activators, and ureadepsipeptide hybrids. Assess their …
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Characterization of the Factors Associated with SCCmec Mobility in Staphylococcus Aureus
… increasing prevalence of methicillin-resistant Staphylococcus aureus infections may be due, in part, to the transfer of SCCmec into successful methicillin-sensitive S. aureus lineages. In this work we attempt to better characterize the factors associated with SCCmec transfer, beginning with …
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Immunogenicity of Staphylococcus Aureus Antigens Against Experimentally Induced Mastitis in the Mouse and Optimization of Antigen Production in Fermenter Culture
Capsular antigens of "Staphylococcus aureus" Smith and 2-8 strains were evaluated for immunogenicity in mice. Cultural conditions necessary for maximum expression of the antigens were also defined. Actively growing "S. aureus" Smith strain culture was used to challenge lactating GF-1 strain mice …
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Patterns and Predictors of HIV, Sexually Transmitted Infections, and Staphylococcus Aureus Co-Infection among New York State Prison Inmates
… communicable diseases. At the same time, Staphylococcus aureus (S. aureus) colonization and infection rates are elevated in these settings. Moreover, HIV and sexually transmitted infections (STIs) are also prevalent. The purpose of this cross-sectional, correlational secondary analysis was …
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Institutional and Patient Level Predictors of Multi-Drug Resistant Healthcare-Associated Infections
Healthcare-associated infections (HAI) caused by multi-drug resistant organisms (MDRO) are an important patient safety concern resulting in a substantial financial and clinical burden. This dissertation aims to contribute to the evidence base on institutional and patient level factors that predict …
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Interactions of Proteins with Membranes: Insights from Molecular Dynamics Simulations
… β-PFTs expressed by the pathogenic bacterium Staphylococcus aureus. The toxin is used by the pathogen to escape the immune system of the host organism, by assembling into octameric transmembrane pores on the surface of the target immune cell and leading to its death by leakage or apoptosis. …