Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 338 for “"Standard of care"”.
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Capsule endoscopy versus standard of care in obscure gastrointestinal bleeding: A randomized controlled trial
… negative, the small bowel could be the source of obscure gastrointestinal bleeding presenting as IDA. The next best diagnostic test is uncertain. Wireless capsule endoscopy (WCE) is a non-invasive new technology that allows examination of the entire small bowel. Methods: We designed a …
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Probiotic Use in Trauma Patients: A Pathway to Determining the Standard of Care to Improve Outcomes
<p>The gut microbiome consists of normally non-pathogenic bacteria, viruses, and fungi. These friendly microbes serve to maintain GI barrier function and integrity, play a role in host nutrient and drug metabolism, immunomodulation, and prevent pathogenic bacteria from colonizing or causing …
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The standard of care and responsibility required of auditors in the detection of fraudulent or illegal activity: the AWA case
The auditor's role in the detection of fraudulent or illegal activities has posed a continuing dilemma. In the 1980's, a lengthy period of large profits made by Bond, Skase and others, was followed by corporate collapses and subsequent findings of significant losses. Recently, the large corporate …
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P4HB TARGETING HALTS TUMOR GROWTH AND RE-SENSITIZES RESISTANT MELANOMA CELLS TO DABRAFENIB AND TRAMETINIB STANDARD-OF-CARE THERAPY VIA IRE1-⍺ ACTIVATION AND AKT DOWNMODULATION
… melanoma patients account for approximately 50% of all cutaneous melanoma cases. The overall survival rate of metastatic melanoma patients was dramatically improved by the introduction of targeted therapy (BRAF and MEK inhibitors) and immune checkpoints inhibitors (anti-PD1, anti-CTLA4). However, …
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International Normalised Ratio Monitoring in Children: Comparing the accuracy of portable point-of-care monitors to standard of care laboratory monitoring at Red Cross War Memorial Children's Hospital
… There is an increasing trend in the use of long-term oral anticoagulation therapy in children. Monitoring the international normalised ratio (INR) is an integral part in management of these patients, but standard laboratory testing of the INR presents challenges in this age group. …
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A Primary Care Intervention for Management of Childhood Obesity
… To support weight control and acquisition of healthy behavior in the families with overweight children, the essential first step is to create and sustain behavior change among the primary care providers (PCP) who are doing the counseling toward a standard of care. Despite regular access to …
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An economic evaluation of task-shifting approaches to the dispensing of anti-retroviral treatment in the Western Cape, South Africa
… assistants] and nurse-based pharmaceutical care models against the standard of care that involves a pharmacist dispensing ART, on the basis of cost, and patient preference.
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Identification and treatment of opioid use disorder in the emergency department
… (ED) settings. This study aimed to introduce a standard of care that incorporates medication-assisted treatment and facilitates referrals for continuous therapy among individuals with OUD seeking assistance in the ED. Methods: A search was conducted on the Cumulative Index to Nursing and Allied …
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Nurse Anesthetists' Perspectives on Multimodal Pain Management
… for nurse anesthetists, there is not a standard of care for addressing postoperative pain management in adult abdominal surgical procedures. Objective: The purpose of the project is to determine the perspectives of nurse anesthetists for developing postoperative pain management in adult …
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Juror decision-making in professional liability cases: A model and tests in the audit litigation setting
Auditors and other professionals currently face a litigation crisis. An important cause of this crisis is that auditors' decision and actions are evaluated in light of an ill-defined standard of care and in hindsight. In this dissertation, I develop a model of juror decision making for professional …
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A pilot study to examine a therapeutic exercise intervention on fibromyalgia symptoms
Objective. To examine the feasibility of a home-based, video therapeutic exercise program on pain, fatigue, self-efficacy, and health status in fibromyalgia patients. Methods. Nine individuals who were previously diagnosed with fibromyalgia completed the study (out of an initial pool of 31). …
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Design of an intraperitoneal drug-release device for advanced ovarian cancer therapy
… States die from ovarian cancer each year. The standard of care is tumor-debulking surgery followed by adjuvant chemotherapy. Combination intraperitoneal (IP) and intravenous (IV) chemotherapy has been shown to lengthen survival over IV therapy alone. Large-volume infusions, drug-associated …
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Exploiting p53 mutation in colorectal cancer: clinical positioning of Cdc7 inhibitors
… in TP53 are present in approximately 50% of colorectal cancer (CRC) and are enriched for in the metastatic setting. As a result of TP53 mutation these tumours are limited in their ability to execute tumour-suppressive functions. Synthetic lethal targeting of pathways/ proteins on which …
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Using urinary MCP-1 and TWEAK to assess disease activity in a cohort of South African patients with lupus nephritis
… lead to chronic kidney disease (CKD). Diagnosis of lupus nephritis (LN) is dependent on renal biopsy. Due to its invasiveness, repeat renal biopsy for monitoring disease activity is not recommended, thus creating a need for noninvasive and accurate biomarkers. Monocyte chemoattractant protein-1 …
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Cultural Competence and End-of-Life Care: Religion, Spirituality and Health Care Decision-Making
The changing demographic of the U.S. population has shed new light on the importance of providing all patients with the highest standard of care possible. An increase in the number of foreign-born residents with diverse religious backgrounds requires health care professionals to know strategies for …
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Development of a NASA Flight Surgeon Quick Reference Guide and Evaluation of the International Space Station Medical Kit: A Model for Resource-Limited Populations
The development of an operational Flight Surgeon Quick Reference Guide to complement on-orbit crewmember medical checklists aims to standardize medical care on the part of NASA’s medical ground support for a unique patient population in an austere environment. Adapting terrestrial clinical …
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Characterising pathways driving aggressive biology and chemoresistance in triple negative breast cancers biology and chemoresistance in triple negative breast cancers
This body of work served to investigate the mechanisms driving chemoresistance in a series of in vitro TNBC cell line models. Molecular characterisation and comparison of drug resistant models allowed for the identification of promising druggable targets, whose efficacy in restoring …
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Outpatient Medication Error Improvement
… -Improving Medication Administration (Outpatient Care)</strong></p> <p><strong>SPECIFIC AIM:</strong> We aim to Improve the medication administration process and involve all staff within 6 months</p> <p>In the microsystem consisting of 14 family practice and urgent care clinics, there is not a …
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The impact of bereavement intervention on levels of grief in pregnant women who experience pre-twenty-week loss
… in six pregnancies is lost before the 20th week of gestation (Craven & Wise, 2002). Such losses can be devastating for the woman and her family. However, the psychological impacts of these losses are frequently not addressed by the health care establishment as attention is focused on the woman's …
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Insights in Depression Screening at a Latino-Serving, Integrated FQHC Clinic
… were performed to determine the effects of ethnicity and language on PHQ-2 screening rates for 10,285 adult patients seen during a primary care medical visit from 2014 to 2015; of these 4,745 (46%) patients were screened for depression. Spanish-speakers were screened for depression more …
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