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Showing 1 to 3 of 3 for “"StARD4"”.
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A Novel Subfamily of Three StAR-Related Lipid Transfer Proteins That Are Differentially-Regulated and Function in Intracellular Cholesterol Metabolism
… cloning, and initial characterization of StarD4, sterol-regulated gene encoding a StAR-related lipid transfer (START) protein, and its close homologues, StarD5 and StarD6. StarD4 was identified using cDNA microarrays, as liver StarD4 expression decreased three-fold in mice fed a high …
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Characterization of the Functional Role of the Intracellular Cholesterol Transporter StARD4 in Knockout Mice, and Investigation of Epigenetic Modulation of ApoA-I Transcription
… or ER stress families of transcription factors. StARD4 is regulated by SREBPs and we have chosen to make a mouse knockout model to characterize its role in-vivo. StARD4, expressed primarily in liver and macrophages, is a known intracellular cholesterol transporter previously shown to be …
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An In Vivo Characterization of the Functional Role of Two Novel Genes: StARD5 and ADAM11
… SREBP-upregulated liver gene StARD4; initial studies indicate that a full StARD4 knockout is viable.</p>