Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Spred"”.
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Identification and characterisation of the Spred protein family
… protein with an EVH-1 domain 1, 2 and 3 (Spred-1, -2, -3)(Wakioka et al, 2001; Kato et al, 2003). Spred-1, -2 and -3 are membrane associated substrates of receptor tyrosine kinases and they act as negative regulators of the Ras pathway during growth factor stimulation. As the Spred-family …
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Generation and characterization of spred-2 knockout mice
Spreds are a new Sprouty-related family of membrane-associated proteins inhibiting the MAPK signaling pathway by interacting with Ras and Raf-1. Different studies have already demonstrated the inhibitory function of Spreds in cell culture systems, but the in vivo function of Spreds in the whole …
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Regulation of FGF Receptor signalling by SPROUTY and SPRED
… poorly defined. Sproutys and their related Spred proteins constitute two such families of signalling regulators with multiple developmental roles as well as potential tumour suppressive functions. However, the molecular mechanisms of these proteins have remained unclear and subject to many …
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The Syntax of the Dialect of Bari
… as a finite form within the periphrasis. This spred further across the neighbouring dialects to include more grammatical persons (3SG/2SG>1SG>3PL>all), as well as past and irrealis paradigms.