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Showing 1 to 20 of 242 for “"Sprague Dawley rats"”.
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Uncertainty Monitoring in Sprague-Dawley Rats (Rattus norvegicus)
… monkey, an orangutan, a dolphin, pigeons, and rats. Previous research with rats has demonstrated inconsistent results (Foote & Crystal, 2007; Smith & Schull, 1989). In the current study, two Sprague-Dawley rats were tested in a tone-length discrimination task in which they were prompted to …
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Uncertainty Monitoring in Sprague-Dawley Rats (Rattus norvegicus)
… monkey, an orangutan, a dolphin, pigeons, and rats. Previous research with rats has demonstrated inconsistent results (Foote & Crystal, 2007; Smith & Schull, 1989). In the current study, two Sprague-Dawley rats were tested in a tone-length discrimination task in which they were prompted to …
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Cell-Mediated Cytotoxicity of Jensen Tumor in Sprague-Dawley Rats
… to the demise of 80% of successfully challenged Sprague-Dawley rats (persistors) while 20% of challenged rats (regressors) destroyed the tumor by an unknown mechanism(s). Lymphocytes from both persistors and regressors were shown to be cytotoxic for tumor cells in vitro. Pretreatment of tumor …
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THE EFFECTS OF ORAL ARGININE ON ITS METABOLIC PATHWAYS IN SPRAGUE-DAWLEY RATS
… 500 mg/kg/day administered for 4 weeks in male Sprague-Dawley rats. The present study examined the effects of oral L-arginine and D-arginine in 9-week-old male Sprague-Dawley rats, administered at a higher dose of 1000 mg/kg/day in drinking water for a longer duration of 16 weeks. We measured …
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Thymoquinone decreases oxidative DNA damage (8-OHdG) in DMBA treated female Sprague Dawley rats
… 8-OHdG and GSH compared with tamoxifen in female Sprague Dawley rats treated with 7,12 dimethylbenz (a)anthracene (DMBA, a drug that induces mammary cancer). 8-OHdG is the most commonly assayed fingerprint of free radical attack on DNA and is involved in tumor progression. Five groups of 10 rats …
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Intratracheal instillation of silver nanoparticles exacerbates cardiac ischemia/reperfusion injury in male sprague-dawley rats
… To test this hypothesis, we exposed male SD rats to an intratracheal (IT) instillation of 200 µg of 20 or 110 nm polyvinylprryolidone (PVP) or citrate capped AgNP, in 200 ul of the respective PVP or citrate vehicle. Serum samples were collected prior to instillation and 1, 3, 6, 24, 48, 72, …
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The effects of zinc intake and exercise on iron status of pregnant Sprague-Dawley rats
… zinc intake and exercise on the iron status of Sprague-Dawley rats during pregnancy were observed. The dams were assigned to one of four groups: zinc marginal (6.18 ppm zinc sulfate), exercise or sedentary; zinc adequate (37.63 ppm), exercise or sedentary. The dams swam everyday for one hour …
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Impact of potato protein supplementation with dietary fermentable materials on immune measures in Sprague-Dawley rats
… affect the immune systems of female and male Sprague-Dawley rats. Gnaw sticks are a common environmental enrichment tool included here to determine whether they could confound experimental results. Potato protein (PP) increased both total short and branched chain fatty acids (SCFA, BCFA) …
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The effects of chrysin on osteoclastogenesis in RAW264.7 murine macrophages and bone metabolism in Sprague Dawley rats
… was utilised to assess the tibia bones in Sprague-Dawley rats. The parameters evaluated of the whole bone, length, volume, surface area, bone volume fraction, segmented surface density, and the thickness, number, and spacing of trabecular bone. The parameters evaluated for the midpoint of …
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Effects of Thyroxine and Propylthiouracil Treatment of Young Male Sprague-Dawley Rats on Potassium-Induced Contraction of Thoracic Aorta
… and propylthiouracil treatment of young male Sprague-Dawley rats on aortic ring contraction induced by increasing potassium concentrations. Procedure. Three groups (N=6) of thirty-day-old male Sprague-Dawley rats were treated for nineteen days with thyroxine (200 micrograms by injection), …
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Dietary vitamin B6 supplementation promotes the growth of 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in Sprague Dawley rats
… (DMBA)-induced mammary carcinoma in rats. Specifically, we aimed to identify the effect of pyridoxine (PN) supplementation on tumor growth and vitamin uptake by tumor cells. To accomplish this, 50 d old female Sprague Dawley rats were gavaged with 15 mg DMBA and fed a diet containing …
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Ameliorative effect of the methanolic Crude extracts of Inula glomerata and Salacia kraussii on erectile dysfunction in Sprague Dawley rats
… radicals. For in vivo studies thirty-five male Sprague Dawley rats were divided into seven groups (with five rats per group). The normal group, n-butanol, n-butanol+ Inula glomerata (50 and 250 mg/kg body weight), n-butanol+ Salacia kraussii (50 and 250 mg/kg body weight) and n-butanol+ Cialis …
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A maternal low-protein diet during gestation induces hepatic autophagy gene expression only in the female offspring Sprague-Dawley rats
… expression in the liver of offspring rats. In this study, pregnant Sprague-Dawley rats were fed either a control diet (18% energy from protein) or a low-protein diet (8.5% energy from protein) during gestation period followed by the control diet during lactation. Offspring consumed the …
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The effect of dietary zinc on induction of cytochrome p-450 by phenobarbital or 3-methylcholanthrene in male Sprague-Dawley rats
… the hepatic microsomal monooxygenase system in Sprague-Dawley rats was investigated in the present study. Three routes of zinc administration—oral gavage, intraperitoneal injection and dietary supplement—were compared for accumulation of zinc in the liver and intestine, and induction of hepatic …
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A STUDY ON THE EFFECTS OF CHRONIC ALCOHOL AND WITHDRAWAL IN THE BASOLATERAL AMYGDALA OF SPRAGUE DAWLEY RATS: AFFERENT SPECIFIC MODIFICATION OF GLUTAMATERGIC NEUROTRANSMISSION
The lateral and basolateral amygdala (BLA) are major amygdala subdivisions that process environmental stimuli in an associative process that ultimately results in anxiety-like or fearful behavioral responses. These nuclei receive glutamatergic input via two major pathways differentiated by their …
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Efficacy of tamoxifen and thymoquinone on tumor development, lipid peroxidation, and total antioxidant capacity in DMBA induced mammary carcinoma in female Sprague-Dawley rats
… antioxidant capacity in DMBA treated female Sprague-Dawley rats. Five groups of 10 rats (control, DMBA, TAM, TQ, and TAM+TQ) were used. Mammary tumors were induced by DMBA which was given by oral gavage to four groups: DMBA, DMBA+ TAM, DMBA+ TQ, and DMBA+ TAM & TQ. The control group received …
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Maternal High-Salt Diet During Pregnancy in Sprague Dawley Rats Programs Exaggerated Stress-Induced Blood Pressure and Heart Rate Responses in Adult Female Offspring
… health. In the present study, pregnant rats were fed a 0.7% NaCl normal salt (NS) diet or an 8% NaCl high salt (HS) diet throughout pregnancy. Adult offspring were fitted with radiotelemetry probes to continuously measure blood pressure and heart rate. Rats were placed in restraining …
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A Study on the Effects of Chronic Alcohol and Withdrawal on the Glutamate, GABA, and Dopamine Systems in the Basolateral Amygdala of Sprague Dawley Rats
… (D3Rs) in the BLA of alcohol-naïve adolescent Sprague Dawley rats can significantly alter anxiety-like behavior. Moreover, these results led us to uncover a functional role of D3Rs at local and LPC synapses as well as a concentration dependent effect of DA at local synapses. Finally, in chapter …
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Effects of oral delta-9-tetrahydrocannibinol (THC) administration on motor activity and anxiety-like behavior in adolescent and adult Sprague-Dawley rats of both sexes
… effect and reduce locomotor activity in rats, but it is unclear if this also occurs following volitional, oral intake of THC. Here, we used adolescent and adult rats of both sexes to determine if oral THC would alter locomotor activity in an open-field arena (OFA) and anxiety-like …
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