Global ETD Search
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Showing 1 to 1 of 1 for “"Spongiform Degeneration"”.
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Dilations of the Endoplasmic Reticulum Contribute to Spongiform Degeneration and Unlock a Door to a Unified Model of Neuropathological Features in Prion Diseases
… neurodegenerative disorders characterized by spongiform degeneration, neuronal loss, and misfolded prion protein (PrPSc) deposition. The mechanistic origins of spongiform degeneration, which manifests as intracellular vacuolation in neurons, have remained unclear. We considered similarities …