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Showing 1 to 11 of 11 for “"Splenectomy"”.
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Splenectomy for immune thrombocytopenia : our 11-year experience
Splenectomy has been practiced for the treatment of ITP for the past few decades. Currently it is utilised when a patient is either dependent or resistant to steroid treatment and the platelet count remains less than 30×109/L. Recently new agents have been added to the armamentarium used to treat …
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Review and re-appraisal of patients treated with splenectomy for immune thrombocytopenic purpura at five years and beyond
The risk of pneumococcal infection post splenectomy is life long so all patients undergoing splenectomy are given polyvalent (23-valent) unconjugated pneumococcal polysaccharide vaccine, preoperatively. The aim of this study was 1. to measure the success of splenectomy at a tertiary institution at …
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Characterization of the Murine Macrophage Suppressor Factor (Msf)
… the activity attributed to MSF can be removed by splenectomy. An in vitro assay was used which allows a determination of the phagocytic rate of the macrophage. The presence of MSF was apparent by noting a reduced phagocytic-rate of adherent peritoneal exudate cells (PEC) between 10-12 days …
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Disease pathogenesis, treatment effectiveness, and co-morbid burden among adult patients with primary immune thrombocytopenia (ITP)
… platelet studies in predicting outcomes from splenectomy 4. To document health-related lifestyle concerns among patients 5. To gauge the effectiveness of Helicobacter pylori (H. pylori) eradication in elevating platelet counts 6. To characterise associations of primary ITP with both arterial …
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The role of substance P in experimental intracerebral haemorrhage.
… barrier integrity). The effect of prior splenectomy on oedema following ICH was also assessed. Results: Elevated levels of SP were demonstrated post-ICH in the two different ICH models, and localised to astrocytes. Following collagenase ICH, two structurally unrelated NK1R antagonists …
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The Ratio of Heinz Body Formation in Different Hemoglobin Zurich Subjects
… as the control. The results collaborate that splenectomy increases the number of erythrocytes containing Heinz bodies in peripheral blood. The menstrual cycle apparently has no statistical affect on the increased ratio of Heinz body-containing erythrocytes to normal erythrocytes.</p>
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B-cell development and function in the absence of the spleen
… serum IgM levels are reduced in Hox11-/- mice. Splenectomy of wild-type mice demonstrated that the spleen is also important for the survival of B-1a cells, as the majority of peritoneal B-1a cells were lost within one week after removal of the spleen. Hox11-/- and splenectomized mice were …
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The use of near infrared spectroscopy in detecting hemorrhagic shock in swine
… method: fresh frozen plasma, cryo, hextand, splenectomy, sham and platlets. The pigs that were bled showed a significant decrease in SmO2 during the controlled hemorrhage at 50% Bleed when compared to Baseline (p less than 0.05). The SmO2 also showed a significant decrease between the end of …
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Changes in peripheral B cell subsets under immunosuppressive therapy
… patients. It has recently been shown that splenectomy and congenital asplenia cause a profound and long-lasting loss of IgM memory B cells together with an impairment of the immune response to pneumococcal polysaccharides. As successful allogeneic stem cell transplantation (allo-SCT) …
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Identification of Novel Allosteric Regulators of Human Erythrocyte Pyruvate Kinase
… are limited to continuous blood transfusions and splenectomy. Thus, there is an urgent need for medications to counter R-PK deficiency without resorting to these complicated procedures. Our aim is to identify novel allosteric modifiers of R-PK using a combination of computational studies and …
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ΕΛΕΓΧΟΣ ΣΠΛΗΝΙΚΗΣ ΔΡΑΣΤΗΡΙΟΤΗΤΟΣ ΚΑΙ ΑΝΟΣΟΛΟΓΙΚΕΣ ΕΠΙΠΤΩΣΕΙΣ ΜΕΤΑ ΣΠΛΗΝΕΚΤΟΜΗ
ΣΤΗ ΒΙΒΛΙΟΓΡΑΦΙΑ ΥΠΑΡΧΕΙ ΔΙΑΣΤΑΣΗ ΑΠΟΨΕΩΝ, ΟΣΟΝ ΑΦΟΡΑ ΤΙΣ ΕΠΙΠΤΩΣΕΙΣ ΤΗΣ ΣΠΛΗΝΕΚΤΟΜΗΣ ΤΡΑΥΜΑΤΙΚΗΣ ΑΙΤΙΟΛΟΓΙΑΣ-ΣΤΟ ΑΝΟΣΟΛΟΓΙΚΟ ΣΥΣΤΗΜΑ. ΣΤΗΝ ΕΡΓΑΣΙΑ ΜΑΣ ΜΕΛΕΤΗΣΑΜΕ ΤΗΝ ΜΕΤΑ ΣΠΛΗΝΕΚΤΟΜΗ ΣΠΛΗΝΙΚΗ ΔΡΑΣΤΗΡΙΟΤΗΤΑ ΚΑΙ ΤΗΝ ΕΠΙΠΤΩΣΗ ΤΗΣ ΣΠΛΗΝΕΚΤΟΜΗΣ ΣΤΟ ΑΝΟΣΟΛΟΓΙΚΟ ΣΥΣΤΗΜΑ. ΜΕΛΕΤΗΘΗΚΑΝ ΣΥΝΟΛΙΚΑ 37 ΑΣΘΕΝΕΙΣ …