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Showing 1 to 1 of 1 for “"Spiro-b-lactone."”.
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Efforts toward an enantioselective total synthesis of (–)-oxazolomycin B and simplified chemical probes for proteomics studies; pharmacophore-directed retrosynthesis applied to gracilin A : simplified bioactive derivatives.
… asymmetric synthetic approaches to the unique spiro- or fused-lactone γ-lactam core structure of these natural products have been reported. To the best of our knowledge no catalytic enantioselective strategies for the synthesis of the densely functionalized oxazolomycin γ-lactam exist in the …