Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Spiny projection neurons"”.
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Understanding the role of striosomes in learning a decision-making task
… images of mice, I find that: 1) the activity of spiny projection neurons (SPNs) in striosomes correlate with learning ability; 2) an animal's attentiveness to the task is critical for learning; 3) anatomical circuit disassembly, specifically reduced connectivity of inhibitory Parvalbumin (PV) …
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Enhanced striatal glutamatergic function upon chronic antipsychotic action
… function. Cell type-specific mRNA profiling on spiny projection neurons (SPNs) of the direct (dSPNs) and indirect (iSPNs) pathways following chronic antipsychotic administration revealed cell type-specific molecular alterations indicating increases in components of the glutamatergic postsynaptic …
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Compensation Between Foxp Transcription Factors Maintains Proper Striatal Function
Spiny projection neurons (SPNs) of the striatum are critical in integrating neurochemical information to coordinate motor and reward-based behavior. Mutations in the regulatory transcription factors expressed in SPNs can result in neurodevelopmental disorders (NDDs). Paralogous transcription …
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Striatal Microcircuits Underlying Control of Actions
… attempted to elucidate the relationship between neurons in the dorsal striatum and movement, the mechanism of how striatal activity in the dorsal striatum contributes to movement velocity remains unclear. One reason is that traditional experimental designs of the basal ganglia have either …