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Showing 1 to 3 of 3 for “"Spinal contusion"”.

  1. A Pre-Clinical Assessment of Minocycline For Treatment of Chronic Neuropathic Pain After Spinal Cord Injury

    <p>Patients living with a spinal cord injury (SCI) often develop chronic neuropathic pain (CNP). Unfortunately, the clinically approved, current standard of treatment, gabapentin, only provides temporary pain relief. This treatment can cause numerous adverse side effects that negatively affect the …

    uthsc Repository record for A Pre-Clinical Assessment of Minocycline For Treatment of Chronic Neuropathic Pain After Spinal Cord Injury (opens in a new tab)

  2. Characterising changes in pathology and function in clinically relevant models of spinal cord injury and using chondroitinase ABC gene therapy to promote repair

    … experimental therapeutic for the treatment of spinal cord injury (SCI). In pre-clinical studies ChABC has repeatedly been shown to enhance functional recovery in a number of SCI models in both rodents and larger animals through its enzymatic degradation of inhibitory chondroitin sulphate …

    kings Repository record for Characterising changes in pathology and function in clinically relevant models of spinal cord injury and using chondroitinase ABC gene therapy to promote repair (opens in a new tab)

  3. Trpv1 Channels Contribute to Behavioral Hypersensitivity and Spontaneous Activity In Nociceptors After Spinal Cord Injury

    <p>A majority of persons who have sustained spinal cord injury (SCI) develop chronic pain. While most investigators have assumed that the critical mechanisms underlying neuropathic pain after SCI are restricted to the central nervous system (CNS), recent studies showed that contusive SCI results in …

    uthsc Repository record for Trpv1 Channels Contribute to Behavioral Hypersensitivity and Spontaneous Activity In Nociceptors After Spinal Cord Injury (opens in a new tab)