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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 36 for “"Spin labeling"”.
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Lipid Spin-Labeling of Hymenolepis Diminuta
Made available in DSpace on 2014-12-11T21:33:49Z (GMT). No. of bitstreams: 1 7412178.pdf: 2023081 bytes, checksum: c6ce8b562453069db32751edbd3d7abb (MD5) Previous issue date: 1973
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Efficiency of background suppression for arterial spin labeling
Arterial spin labeling (ASL), a technique developed for the measurement of local tissue perfusion with MRI, is heavily dependent on distinguishing irrelevant static tissue signal from the labeled blood. Background suppression can greatly reduce motion and other sources of noise in Arterial Spin …
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DEVELOPMENT OF IMPROVED ARTERIAL SPIN LABELING METHODS IN HUMANS AND ANIMAL MODELS
Arterial spin labeling (ASL) is an important tool in evaluating cerebral blood flow (CBF), with applications in clinical imaging for brain tumors and stroke, and as a research tool for brain injury and Alzheimers disease. Multi-TI ASL makes it possible to measure CBF and arterial transit time …
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Measurement of Cerebral Blood Flow Using Arterial Spin Labeling Magnetic Resonance Imaging
… non-invasively. Pseudo-Continuous Arterial Spin Labeling (pCASL) MRI is a new MRI technique that is able to detect blood flow changes, non-invasively. The blood flow change detected by pCASL MRI is relative and it is expressed in terms of arbitrary MRI units which does not have any …
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Improving the Robustness of Perfusion Imaging with Arterial Spin Labeling Magnetic Resonance Imaging
… A new class of technique, known as arterial spin labeling (ASL), uses the water molecules in the arterial blood as an endogenous tracer to measure CBF via magnetic resonance imaging. ASL is therefore completely non-invasive and has been widely adapted in both clinical and research …
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Perfusionsmessungen am menschlichen Herzen mit der Magnetresonanztomographie - Quantifizierung mit der Spin-Labeling-Technik
… quantitativ beschreiben. Mit der Spin Labeling Methode können T1-Werte nach globaler und schicht-selektiver Sättigung bestimmt werden. So lassen sich nach einem Zwei- Kompartimente-Modell Absolutwerte für die myokardiale Perfusion berechnen. In der vorliegenden Arbeit wurden …
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Quantifizierung der Perfusion mit Arterial Spin-Labeling Techniken in der Magnetresonanz-Tomographie an Hand eines Perfusionsphantoms
Die Arterial Spin-Labeling Technik ermöglicht eine nicht-invasive Perfusionsbestimmung ohne Kontrastmittelgabe mittels Magnetresonanz-Tomographie. Im Rahmen dieser Arbeit wurde erstmalig ein MR-kompatibles künstliches Perfusionsphantom entwickelt und erprobt, mit dem ein Perfusions-Goldstandard in …
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Metal dependent structure, dynamics, and function in RNA measured by site-directed spin labeling and EPR spectroscopy
… methods. In this study, using site-directed spin labeling (SDSL) and EPR spectroscopy, distances in RNA duplexes, TAR RNA, and the hammerhead ribozyme have been measured to investigate RNA structures. Kinetic measurements have been performed in the extended hammerhead ribozyme to correlate …
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A study of SecA : the motor of the bacterial secretion system by site-directed spin labeling and EPR
… resonance (EPR) spectroscopy and site-directed spin labels at a multitude of sites on the surface of the 102 kDa SecA protein. EPR spectroscopy is sensitive to changes in the local environment of the spin label, and thus our survey of the SecA surface provided a map of interaction sites with its …
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Accuracy of pulsed arterial spin labeling magnetic resonance imaging in the human brain : tag width and timing effects
Arterial spin labeling (ASL) is the only non-invasive magnetic resonance imaging (MRI) technique that allows absolute quantification of cerebral blood flow (CBF). It involves using radiofrequency pulses designed to invert the spins of water in arterial blood, effectively creating a magnetic bolus. …
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Die Durchblutung des menschlichen Herzmuskels : quantitative Bestimmung in vivo mittels Kernspintomographie
… zwei Ansätze verfolgt, das kontrastmittelfreie Spin-Labeling Verfahren und die kontrastmittelgestützte First-Pass Messung
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Die Bestimmung der Änderung des Sauerstoffverbrauchs unter funktioneller Aktivierung mittels Kernspintomographie
… of blood flow changes are obtained by arterial spin labeling. Changes in venous blood oxygenation are measured with the help of the dependence of the BOLD effect on venous blood oxygenation and the blood volume CBV. The combination of the arterial spin labeling technique with an EPI-module for …
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Investigating Ligand Induced Conformational Changes in the Estrogen Receptor
… using the reporter group method of site-directed spin labeling (SDSL), along with electron paramagnetic resonance (EPR) spectroscopy. In this work, B and C parameter calculations from EPR line-shape theory express receptor differences quantitatively as a spectrum of conformational change. Relative …
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Cerebral Blood Flow, Fitness and Behaviour Changes With a High Intensity, Socially Engaging Physical Activity Program for Young Adults With Autism Spectrum Disorder
… weekly unsupervised, MVPA intervention. Arterial spin labeling (ASL), fitness testing, and diagnostic measurements gauged changes in CBF, fitness, and behaviors respectively. Statistical significance (p<0.05) was found in the Autism Diagnostic Observation Schedule (ADOS II) (pre mean=14.58, sd …
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Phase-based regional oxygen metabolism in magnetic resonance imaging at high field
… used standard gradient-echo (GRE) and arterial spin labeling (ASL) to make these measurements. Results for in vivo Y, and CMRO₂ estimates on human subjects are presented from application of our technique at 3 Tesla (3T). We also extended our method to high-field human imaging at 7 Tesla (7T), …
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Magnetic resonance imaging of the cerebral metabolic rate of oxygen (CMRO₂)
… in QUIXOTIC is the use of velocity-selective spin labeling to isolate MR signal exclusively from post-capillary venular blood on a voxel-by-voxel basis. This isolated signal can be related to venular oxygen saturation, oxygen extraction fraction, and ultimately CMRO₂. This thesis first …
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Quantification of Myocardial Perfusion Based on Signal Intensity of Flow Sensitized MRI
… of measuring cardiac perfusion by arterial spin labeling, the relative difference in the apparent T1 relaxation times in response to selective and non-selective inversion of blood entering the region of interest is related to perfusion via a two-compartment tissue model. But accurate …
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Pseudo Random Arterial Modulation (PRAM): A Novel ASL Approach to Measure Flow and Blood Transit Times
… blood using radio frequency (RF) pulses at a labeling plane inferior to the imaging plane. A series of images are taken at the imaging plane and flow reconstructed from the transit time measurements. PRAM does not require separate control and label acquisition as is common in Arterial Spin …
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Anatomische und funktionelle Magnetresonanztomographie der menschlichen Lunge
… Perfusionsmapping-Technik mittels Protonen-Spin-Labeling, ohne Verwendung eines intravenösen Kontrastmittels wie Gadolinium (Gd)-DTPA, vorgestellt. Aus einer nicht-schichtselektiven (globalen) T1-Map und einer schichtselektiven T1-Map derselben Lungenschicht, die jeweils mit der oben …
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Machine Learning Classification of Traumatic Brain Injury Patients Versus Healthy Controls Using Arterial Spin Labeled Perfusion MRI
… neuroimaging techniques such as arterial spin labeling (ASL) can noninvasively assess cerebral blood flow (CBF) changes observed post-injury, this technique is underutilized in TBI research partly due to the low signal-to-noise-ratio (SNR) inherent in ASL imaging. The aim of the current …
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