Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Specificity Protein 1"”.
-
Specificity protein 1 induces the expression of angiomotin in response to IL-6/STAT3 activation to mediate YAP-dependent growth of breast cancer cells
… of transcriptional co-activator yes associated protein (YAP), implicating IL-6 in the co-activation of several transcription factors such as the TEADs that trigger pro growth programs. While IL-6/STAT3 stimulation has been shown to increase YAP activity, the mechanism driving this remains …
-
Targeted Inhibition of Sp1 Transcription Factor and Anti-Angiogenesis of Human Pancreatic Cancer
<p>Transcription factor Specificity Protein 1(Sp1) is reported to be essential for vascular endothelial growth factor (VEGF) constitutive expression in human pancreatic adenocarcinoma. The definitive role of Sp1 in angiogenesis, the impact of anti-angiogenic therapy on the Sp1/ VEGF signaling and …
-
Leptin and peroxisome proliferator activated receptor alpha: understanding their contribution towards normalising the programmed phenotype in the peripheral tissues of IUGR offspring
… palmitoyl transferase-1 (CPT-1) and lipoprotein lipase (LPL).<br/><br/>Real time PCR indicated that the expression of several key genes involved in energy balance, including PPAR?, PPAR? and their target genes, was not altered by maternal diet or postnatal diet in the liver or adipose …