Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Species difference"”.
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GDF9 and BMP15: species difference and synergistic interactions.
… factors which impact their efficiency, including species difference of the proteins, GDF9/BMP15 interactions and the presence of post-translational modifications. However, factors such as species difference and post-translational modifications have yet to be investigated in terms of their effects …
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Metabolic Factors Determining Outcome in Chemotherapy: Studies with Pazopanib
… the work detailed in this thesis assesses differences in the pharmacokinetic profile of pazopanib in various humanised and knock out animal models, as well as differences in toxicological responses. Furthermore, this project looks at variations in the efficacy of pazopanib in syngeneic …
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The biological properties of three trichothecene mycotoxins produces by fusaris
… thymus, spleen and lymph nodes. The reported species difference in T-2 toxin toxicity was investigated by determining the deacylation rate of T-2 toxin to HT-2 toxin, one of the first steps in the detoxification of this trichothecene. The high deacylation rate catalysed by rat microsomes …
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Photoperiodism in the ewe: Endogenous circannual rhythms and olfactory mechanisms influencing reproductive activity
… and timing of reproductive activity in this species is thought to result from the complex interplay of endogenously generated rhythms with exogenous factors including photoperiod and social cues. These studies evaluated whether the expression of circannual rhythms is photoperiod-dependent and …
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Factors Affecting the Kinetics of Light Intensity Adaptation in Marine Phytoplankton
… cycle, nutrient concentration, growth rate and species difference on the photoadaptation kinetics of marine phytoplankton in a series of light transition experiments. The study found that: (1) Hysteresis of photoadaptive response exists between the two reciprocal (low-to-high vs high-to-low) …
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An assessment of endocrine disrupting potential of a New Zealand pulp and paper mill effluent using rainbow trout Oncorhynchus mykiss and mosquitofish Gambusia affinis
… reproductive-endocrine impacts on two fish species, rainbow trout and mosquitofish using a combined approach of laboratory and on-site mesocosm exposures. Rainbow trout Oncorhynchus mykiss were utilised in a combination of early life stage and juvenile (+1 year) long- and short term …
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Estimating Site Productivity from Non-Site Trees: A Site Index Based Approach
… investigate whether a quantitative variable for species tolerance would allow analyses of pooled data in order to increase sample size. Stem analysis data from site and non-site trees was gathered on 100 sites located throughout NW Montana. Species included ponderosa pine, Douglas-fir, lodgepole …
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Estimating Site Productivity from Non-Site Trees: A Site Index Based Approach
… investigate whether a quantitative variable for species tolerance would allow analyses of pooled data in order to increase sample size. Stem analysis data from site and non-site trees was gathered on 100 sites located throughout NW Montana. Species included ponderosa pine, Douglas-fir, lodgepole …
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Geological Control of Floristic Composition in Amazonian Forests
… difficult to study, however, due to their species richness and inaccessibility. This has limited efforts to produce the accurate, high-resolution biodiversity maps needed for conservation and development. The aims of the research described here were to identify efficient solutions to the …
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Characterization of the Beta-2 Adrenergic Receptor Mechanism in Bovine Neutrophils, and Some Effects of Inflammatory Stimuli on its Function
… inflammatory activity, including reactive oxygen species production, chemotaxis, degranulation, and inflammatory mediator production. Dysfunction of beta-adrenergic receptors is known to contribute to the pathophysiology of numerous diseases in both people and animals. For example, congestive …
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Challenges in the Pharmacokinetics of Therapeutic Proteins
… of fully-human mAbs. However, regardless of the species difference in physiology, body weight should be considered during dosage regimen design, especially for pediatric patients who show a highly dynamic change in body size at early age.</p> <p>In summary, the findings in this dissertation have …
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Investigating mechanisms of ovotoxicity of Perfluorooctanoic acid and Zearalenone exposure and the influence of altered metabolic status on ovarian function
… in obese rats was conducted and potential species differences in obesity-induced altered ovarian function related to ovotoxicant exposure were identified (Chapter 2). While no impacts of obesity on several markers of DNA damage were noted, LC-MS/MS analysis provided mechanistic insight into …