Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Spatial memories"”.
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Multiple spatial memories in the brain : decoding and modification using microstimulation
… trained monkeys to remember the location of two spatial cues over a brief delay, and then make two eye movements to the remembered locations in the order that they appeared. We explored the role of two different frontal eye movement areas, the frontal and supplementary eye fields (FEF and SEF) …
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The role of expertise, semantics, and learning in spatial memory
… by examining a recently reported phenomenon of spatial memory, that of exclusivity. Exclusivity states that given the opportunity to encode or retrieve two spatial memories, only one memory is relied upon for object location. This implies that two memories for where an object is located are not …
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Impaired and enhanced spatial representation of the PSD-95 knockout mouse
… preserving two PDZ binding domains causes a spatial learning and memory deficit and a dramatic enhancement of synaptic strengthening. Long Term Potentiation is enhanced at all frequencies of stimulation (1-100Hz), while Long Term Depression is absent in the mutants. This study explores CA1 …
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Encoding and recall of memory for reward location in the mouse hippocampus
… animal’s survival. Encoding and recall of these spatial memories involves the hippocampus, but whether and how hippocampal activity integrates memories of spatial relationships and locations is poorly understood. This thesis investigates how hippocampal activity facilitates the encoding of reward …
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Neural mechanisms involved in memory formation and retrieval within the rodent hippocampus : an in vivo electrophysiological study
… a crucial role in the formation and retrieval of spatial memories, the neural mechanisms underlying this process have not been completely characterized. In this thesis I have combined large-scale recordings from multiple single cells within the hippocampus of behaving rodents with pharmacological …
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Investigating Spatial Memory Reconsolidation in Rats: Memory Updating, Effects of Aging, and Hippocampal Network Activity
Upon acquisition, memories undergo an initial stabilization, or consolidation, process after which they are generally resistant to interference. There is now an abundance of evidence that reactivation or retrieval of a consolidated memory opens up a window of time during which the memory can be …
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The Medial Entorhinal Cortex's role in temporal and working memory : characterization of a mouse lacking synaptic transmission in Medial Entorhinal Cortex Layer III
… understanding how declarative and episodic-like memories are formed. This work here addresses the role of the medial entorhinal cortex layer III (MEC-III) to CA1 projections in episodic-like memory formation and recall. This circuit is addressed with a triple transgenic mouse which allows for the …
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Optogenetic dissection of the dopaminergic circuitry involved in memory consolidation
… circuitry that modulates persistence of everyday spatial memories. The task involved learning a win-stay rule with the daily goal of finding the location of food in the event arena. Using the developed task, it was confirmed that unrelated novel experiences can facilitate the persistence of …