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Showing 1 to 1 of 1 for “"SpAAC reaction"”.
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Development of Novel Chemical Biology Tools for Probing Structure-Function Relationships in G Protein-Coupled Receptors
… strain-promoted [3+2] azide-alkyne cycloaddition reaction (SpAAC) between dibenzocyclooctyne (DIBO) and p-azido-L-phenylalanine (azF) was shown to be a suitable strategy for attaching labels to GPCRs. While characterizing the specificity, kinetics, topology-dependent reactivity of the labeling …