Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Sox-2"”.
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Analyses of hematopoiesis and lineage commitment from ES and iPS cells
… durch ektopische Expression von Sox-2, Oct-4 und Klf-4 generiert worden waren, aufgrund ihres epigenitischen Gedächtnisses in vitro effizienter in hämatopietische Zellen differenzieren als ES-Zellen. Erstaunlicherweise war die Effizienz der Differenzierung von iPS-Zellen im …
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Environmental Impacts of Future Aviation Propulsion Systems
… formation from aviation-attributable NOx and SOx, 2) the technical extent to which the air quality and climate impacts of aviation can be minimized, and 3) how propulsion system design for supersonic commercial aircraft in the future would impact the environment. I first address how emissions …
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Roles of Nanog, a transcription factor for self-renewal of embryonic stem cells, in prostate tumor initiation and chemoresistance
… cells is unknown. Nanog, along with Oct3/4 and Sox-2, constitute the core transcriptional circuitry for the maintenance of stemness in embryonic stem cells. Herein we report that Nanog expression was detected at mRNA and protein levels in prostate cancer cells. The Nanog-expressing LNCaP-T and …
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Inhibition of pancreatic cancer progression through EMT inhibition and induction of ER stress
… 5). Further studies found that b-catenin, Sox-2, and TP53 protein levels were also decreased by C150 treatment. Data revealed that C150 increased proteasome activity by inducing ER stress and triggering UPR. The increased proteasome activity was due to enhanced proteasome assembly but not …
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Oct4 and Sox2 regulate methylation at the Igf2/H19 imprinting control region
… that allowed cooperative binding of Oct4 and Sox2 in vitro. To determine at which developmental stage the octamers regulate ICR methylation, we created a knock-in mouse with mutations in the ICR that eliminate Oct4 binding. Maternal transmission of this mutant allele resulted in partial …